Results 41 to 50 of about 4,194 (248)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Evolution Behavior of Mixed Higher Order Optical Vortex–Edge Dislocations Propagating Through Atmospheric Turbulence

open access: yesIEEE Photonics Journal, 2018
We model the effect of the off-axis distance of edge dislocation on the transmission of mixed higher order optical vortex–edge dislocations in atmospheric turbulence.
Penghui Gao   +4 more
doaj   +1 more source

Singularities of Partially Polarized Vortex Beams

open access: yesFrontiers in Physics, 2020
Singularities in the polarization state of non-uniform electromagnetic beams have been a topic of both theoretical and practical interest for many years, as have singularities in the correlation functions of random scalar wavefields.
William Scott Raburn, Greg Gbur
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Generalized Antiorthotomics of (n, m)-Cusp Curves

open access: yesMathematics
In optics, light rays emitted from a light source form a wavefront (orthotomic) upon reflection by a mirror. The mirror is referred to as an antiorthotomic of the orthotomic.
Qiming Zhao   +3 more
doaj   +1 more source

Statistical studies on optical vortices in dynamic speckle fields

open access: yesJournal of Biomedical Photonics & Engineering, 2018
New parameters to statistically describe and differentiate between different decorrelation behaviors in dynamic speckle fields are described. These decorrelation behaviors are surrogate descriptors of the dynamics of the underlying processes in object ...
Anindya Majumdar, Sean J. Kirkpatrick
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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