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The Development of the Sinoatrial Node
1978In contrast to the many investigations devoted to the morphological development of the atrioventricular specialized tissues (see James, 1970; Anderson and Taylor, 1972 for review) few researchers have studied the development of the sinoatrial node. Amongst the reports existing on this subject, descriptions of the initial histological differentiation of
Robert H. Anderson +3 more
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Histamine and pacemaker shift in the sinoatrial node
Agents and Actions, 1994We used the isolated superfused preparations of right atrium with the zone of the sinoatrial node of rabbits to study the effects of histamine on the location of the dominant pacemaker. The preparations were cut into four pieces and electrical activity was recorded in each fragment by means of a surface suction electrode with internal KCl perfusion ...
E, Kevelaitis +2 more
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1976
The impulse for the activation of the heart is generated normally in the sinoatrial node (SA node). This structure covers an area of only a few square millimeters. The cells have an irregular contour and are small (diameter less than 10 μ). Furthermore, they contain sparse myofilaments which are often not well organized. The intercellular junctions are
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The impulse for the activation of the heart is generated normally in the sinoatrial node (SA node). This structure covers an area of only a few square millimeters. The cells have an irregular contour and are small (diameter less than 10 μ). Furthermore, they contain sparse myofilaments which are often not well organized. The intercellular junctions are
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If and sinoatrial node pacemaking
2004The majority of Na+ channels in the heart are composed of the tetrodotoxin (TTX)-resistant (KD, 2-6 μM) Nav1.5 isoform; however, recently it has been shown that TTX-sensitive (KD, 1-10 nM) neuronal Na+ channel isoforms (Nav1.1, Nav1.3 and Nav1.6) are also present and functionally important in the myocytes of the ventricles and the sinoatrial (SA) node.
A. Bucchi, M. Baruscotti, D. DiFrancesco
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[The effect of aminophylline on the sinoatrial node].
Casopis lekaru ceskych, 1994The objective of the submitted prospective study was to assess the influence of intravenously administered aminophylline on the sinoatrial node. The authors examined by electrophysiological methods 20 patients (16 without dysfunction of the sinoatrial node and 4 with dysfunction of the sinoatrial node).
J, Pella +4 more
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The Sinoatrial Node and Its Dysfunction
1987The purpose of this chapter is to review the function and dysfunction of the sinoatrial node (SAN). The majority of the chapter encompasses SAN dysfunction: surface electrocardiography; clinical manifestations; noninvasive evaluation; intracardiac electrophysiology and treatment.
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Mechanisms of Sinoatrial Node Dysfunction in Heart Failure With Preserved Ejection Fraction
Circulation, 2022Thassio Mesquita +2 more
exaly