Results 11 to 20 of about 70,541 (271)

Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity [PDF]

Frontiers in Cardiovascular Medicine, 2021
The understanding of the electrophysiological mechanisms that underlie mechanosensitivity of the sinoatrial node (SAN), the primary pacemaker of the heart, has been evolving over the past century.
Daniel Turner, Chen Kang, Pietro Mesirca, Juan Hong, Matteo E. Mangoni, Alexey V. Glukhov, Rajan Sah   +6 more
doaj   +6 more sources

Lithium-Induced Sinoatrial Node Dysfunction. [PDF]

Cureus, 2021
Lithium is a common mood-stabilizing drug for manic patients. We describe a case of sinoatrial node dysfunction in a patient with serum lithium levels within the therapeutic range. Given the symptomology and severity of the patient’s illness, after placing a permanent pacemaker, the patient was discharged on the preadmission dose of lithium.
Sarangi A, Javed S, Paul T, Amor W.
europepmc   +4 more sources

Sinoatrial Node Entrance Block [PDF]

Circulation, 1973
Peter Fleischmann
openalex   +4 more sources

Genetics of sinoatrial node function and heart rate disorders

Disease Models & Mechanisms, 2023
Lieve E. van der Maarel, Alex V. Postma, Vincent M. Christoffels   +2 more
doaj   +2 more sources

Myoarchitecture of the Sinoatrial Node and its Relevance for Catheter Ablation: Anatomy and Histology. [PDF]

JACC Case Rep
Restrepo AJ, Razminia M, Sánchez-Quintana D, Cabrera JÁ.   +3 more
europepmc   +3 more sources

Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis

Journal of Cardiovascular Development and Disease, 2021
Cardiac pacemaker cells located in the sinoatrial node initiate the electrical impulses that drive rhythmic contraction of the heart. The sinoatrial node accounts for only a small proportion of the total mass of the heart yet must produce a stimulus of ...
Marietta Easterling, Simone Rossi, Anthony J Mazzella, Michael Bressan   +3 more
doaj   +1 more source

A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C: Phenotyping working group of the ILAE/AES joint translational task force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski, Julika Pitsch, Aristea S. Galanopoulou, Rüdiger Köhling   +3 more
wiley   +1 more source

Cycle length restitution in sinoatrial node cells: a theory for understanding spontaneous action potential dynamics. [PDF]

PLoS ONE, 2014
Normal heart rhythm (sinus rhythm) is governed by the sinoatrial node, a specialized and highly heterogeneous collection of spontaneously active myocytes in the right atrium.
Patric Glynn, Birce Onal, Thomas J Hund
doaj   +1 more source

Junctional Pacemaker May Replace the Sinoatrial Node

Cardiovascular Innovations and Applications, 2021
Junctional rhythm is usually seen in the clinic with different causes. We report a case of bicuspid aortic valve accompanied by sinoatrial node dysfunction.
Min Lin, Yuqin Xiong, Yipin Lin, Yuhua Li, Lijuan Zhang   +4 more
doaj   +1 more source

Comparing the effects of intravenous injection and intranasal atomisation of detomidine in sheep

Veterinary Medicine and Science, Volume 9, Issue 1, Page 353-362, January 2023., 2023
This paper compares the intravenous and intranasal routs of Detomidine administration in sheep. Abstract Background Detomidine is an α‐2 agonist sedative drug which reduces the release of norepinephrine in nerves. Administering this drug through intranasal (IN) route could cause direct transmission to the central nervous system.
Touran Tahmasbi, Abbas Raisi, Amir Zakian, Majid Khaldari   +3 more
wiley   +1 more source