Results 11 to 20 of about 11,359 (232)
Genetics of sinoatrial node function and heart rate disorders
Disease Models & Mechanisms, 2023 Lieve E. van der Maarel +2 more
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Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis
Journal of Cardiovascular Development and Disease, 2021 Cardiac pacemaker cells located in the sinoatrial node initiate the electrical impulses that drive rhythmic contraction of the heart. The sinoatrial node accounts for only a small proportion of the total mass of the heart yet must produce a stimulus of ...
Marietta Easterling +3 more
doaj +1 more source
Cycle length restitution in sinoatrial node cells: a theory for understanding spontaneous action potential dynamics. [PDF]
PLoS ONE, 2014 Normal heart rhythm (sinus rhythm) is governed by the sinoatrial node, a specialized and highly heterogeneous collection of spontaneously active myocytes in the right atrium.
Patric Glynn, Birce Onal, Thomas J Hund
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Junctional Pacemaker May Replace the Sinoatrial Node
Cardiovascular Innovations and Applications, 2021 Junctional rhythm is usually seen in the clinic with different causes. We report a case of bicuspid aortic valve accompanied by sinoatrial node dysfunction.
Min Lin +4 more
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Lithium-Induced Sinoatrial Node Dysfunction [PDF]
Cureus, 2021 Lithium is a common mood-stabilizing drug for manic patients. We describe a case of sinoatrial node dysfunction in a patient with serum lithium levels within the therapeutic range. Given the symptomology and severity of the patient's illness, after placing a permanent pacemaker, the patient was discharged on the preadmission dose of lithium.
Ashish Sarangi +3 more
openaire +2 more sources
Telocytes in the human sinoatrial node [PDF]
Journal of Cellular and Molecular Medicine, 2017 AbstractThe sinoatrial node (SAN) is composed mostly of pacemaker, transitional and Purkinje‐like cells. Pacemaker cells, especially in the centre of the SAN, are surrounded by dense fibrous tissue and do not have any contact with transitional cells. We hypothesize that the SAN contains telocytes that have contacts with pacemaker cells and contractile ...
Lubov B. Mitrofanova +3 more
openaire +3 more sources
Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix. [PDF]
PLoS ONE, 2017 Extracellular matrix plays a role in differentiation and phenotype development of its resident cells. Although cardiac extracellular matrix from the contractile tissues has been studied and utilized in tissue engineering, extracellular matrix properties ...
Jessica M Gluck +8 more
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Sinoatrial-Node Entrance Block [PDF]
Circulation, 1971 Sinus-node function was characterized in 13 patients during cardiac catheterization by the introduction of progressively premature atrial depolarizations. Curves relating the extent of sinus-node depression following these premature depolarizations and their degree of prematurity were constructed.
Bruce N. Goldreyer, Anthony N. Damato
openaire +3 more sources
Bioscience Journal, 2020 Canine distemper is a viral disease that affects several systems on dogs, among them, the cardiovascular system. The aim of this study was to identify canine distemper virus (CDV) in the sinoatrial node (SAN) of dogs serologically positive for distemper
José Eugenio Diniz Bastos +4 more
doaj +3 more sources
Brazilian Journal of Anesthesiology, 2022 Background: Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. The complete mechanism through which Dex induces bradycardia has not been elucidated.
Yong-Qiang Yin +3 more
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