Results 21 to 30 of about 12,234 (213)
Bioscience Journal, 2020 Canine distemper is a viral disease that affects several systems on dogs, among them, the cardiovascular system. The aim of this study was to identify canine distemper virus (CDV) in the sinoatrial node (SAN) of dogs serologically positive for distemper
José Eugenio Diniz Bastos +4 more
doaj +3 more sources
Sinoatrial-Node Entrance Block [PDF]
Circulation, 1971 Sinus-node function was characterized in 13 patients during cardiac catheterization by the introduction of progressively premature atrial depolarizations. Curves relating the extent of sinus-node depression following these premature depolarizations and their degree of prematurity were constructed.
B N, Goldreyer, A N, Damato
openaire +2 more sources
Telocytes in the human sinoatrial node [PDF]
Journal of Cellular and Molecular Medicine, 2017 AbstractThe sinoatrial node (SAN) is composed mostly of pacemaker, transitional and Purkinje‐like cells. Pacemaker cells, especially in the centre of the SAN, are surrounded by dense fibrous tissue and do not have any contact with transitional cells. We hypothesize that the SAN contains telocytes that have contacts with pacemaker cells and contractile ...
Lubov B. Mitrofanova +3 more
openaire +2 more sources
Brazilian Journal of Anesthesiology, 2022 Background: Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. The complete mechanism through which Dex induces bradycardia has not been elucidated.
Yong-Qiang Yin +3 more
doaj +1 more source
Generation of a human embryonic stem cell line (WAe009-A-78) carrying homozygous TBX18 knockout
Stem Cell Research, 2022 T-Box Transcription Factor 18 is a member of the T-box family, encoding TBX18 protein. As a transcriptional repressor, it related to developmental processes of a majority of tissues and organs and plays crucial part in the embryonic development of ...
Qi Xu +5 more
doaj +1 more source
Lithium-Induced Sinoatrial Node Dysfunction [PDF]
Cureus, 2021 Lithium is a common mood-stabilizing drug for manic patients. We describe a case of sinoatrial node dysfunction in a patient with serum lithium levels within the therapeutic range. Given the symptomology and severity of the patient's illness, after placing a permanent pacemaker, the patient was discharged on the preadmission dose of lithium.
Sarangi, Ashish +3 more
openaire +2 more sources
Emerging Signaling Regulation of Sinoatrial Node Dysfunction. [PDF]
Curr Cardiol Rep, 2023 PURPOSE OF REVIEW: The sinoatrial node (SAN), the natural pacemaker of the heart, is responsible for generating electrical impulses and initiating each heartbeat.
Zheng M, Erhardt S, Cao Y, Wang J.
europepmc +2 more sources
Computer Modelling of the Sinoatrial Node [PDF]
Medical & Biological Engineering & Computing, 2006 Over the past decades patch-clamp experiments have provided us with detailed information on the different types of ion channels that are present in the cardiac cell membrane. Sophisticated cardiac cell models based on these data can help us understand how the different types of ion channels act together to produce the cardiac action potential.
openaire +4 more sources
Microvascular Rarefaction in the Sinoatrial Node: A Potential Mechanism for Pacemaker Dysfunction in Early HFpEF. [PDF]
JACC Clin ElectrophysiolManning D +12 more
europepmc +2 more sources
Journal of Pharmacological Sciences, 2005 Calcium channels are essential for excitation-contraction coupling and pacemaker activity in cardiac myocytes. While L-type Ca2+ channels (LCC) have been extensively studied, functional roles of T-type channels (TCC) in native cardiac myocytes are still ...
Kyoichi Ono, Toshihiko Iijima
doaj +1 more source