Results 21 to 30 of about 1,321,275 (276)

Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas

bioRxiv, 2020
Cardiac function is under exquisite intrinsic cardiac neural control. Neuroablative techniques to modulate control of cardiac function are currently being studied in patients, albeit with variable and sometimes deleterious results.
Peter Hanna, M. Dacey, J. Brennan, Alison Moss, Shaina Robbins, Sirisha Achanta, Natalia P. Biscola, M. A. Swid, Pradeep S. Rajendran, Shumpei Mori, Joseph E. Hadaya, Elizabeth H. Smith, Stanley G. Peirce, Jin Chen, L. Havton, Z. Cheng, R. Vadigepalli, J. Schwaber, R. Lux, I. Efimov, J. Tompkins, D. Hoover, J. Ardell, K. Shivkumar   +23 more
semanticscholar   +1 more source

Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons

Protein & Cell, 2021
Activation of the heart normally begins in the sinoatrial node (SAN). Electrical impulses spontaneously released by SAN pacemaker cells (SANPCs) trigger the contraction of the heart. However, the cellular nature of SANPCs remains controversial.
Dandan Liang, Zhigang Xue, Jinfeng Xue, Duanyang Xie, Ke Xiong, Huixing Zhou, Fulei Zhang, Xuling Su, Guanghua Wang, Qicheng Zou, Yi Liu, Jian Yang, Honghui Ma, Luying Peng, C. Zeng, Gang Li, Li Wang, Yi-Han Chen   +17 more
semanticscholar   +1 more source

Digital Technologies in Providing Development of Algorithms Surgical Treatment of Supraventricular Arrhythmias [PDF]

, 2006
The aim of the study was the development and clinical application of patient selection algorithm for surgical treatment of longlasting persistent atrial fibrillation. The study included 235 patients with acquired heart disease and coronary artery disease,
Melo, Benussi, Chang, Fareh, Elvan, Gomes, Lee, Peretto, Saksena, Teh, Nemkov, Je, Evtushenko, Pasic, Saksena, Yeh, Nath, Evtushenko, Evtushenko, Evtushenko, Swanson, La Meir, Saliba, Wenning, Nasso   +24 more
core   +3 more sources

Neurohumoral Control of Sinoatrial Node Activity and Heart Rate: Insight From Experimental Models and Findings From Humans

Frontiers in Physiology, 2020
The sinoatrial node is perhaps one of the most important tissues in the entire body: it is the natural pacemaker of the heart, making it responsible for initiating each-and-every normal heartbeat.
Tatiana M. Vinogradova, T. A. Quinn, Eilidh A MacDonald, Robert A. Rose   +3 more
semanticscholar   +1 more source

cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells

Nature Communications, 2020
It is highly debated how cyclic adenosine monophosphate-dependent regulation (CDR) of the major pacemaker channel HCN4 in the sinoatrial node (SAN) is involved in heart rate regulation by the autonomic nervous system.
S. Fenske, Konstantin Hennis, R. Rötzer, Verena F Brox, E. Becirovic, Andreas Scharr, Christian Gruner, Tilman Ziegler, Verena Mehlfeld, J. Brennan, I. Efimov, A. Pauža, M. Moser, C. Wotjak, C. Kupatt, Rasmus Gönner, Rai Zhang, Henggui Zhang, X. Zong, M. Biel, C. Wahl-Schott   +20 more
semanticscholar   +1 more source

Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis

Journal of Cardiovascular Development and Disease, 2021
Cardiac pacemaker cells located in the sinoatrial node initiate the electrical impulses that drive rhythmic contraction of the heart. The sinoatrial node accounts for only a small proportion of the total mass of the heart yet must produce a stimulus of ...
M. Easterling, Simone Rossi, A. Mazzella, Michael C. Bressan   +3 more
semanticscholar   +1 more source

Are physiological oscillations physiological?

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Atrial and Sinoatrial Node Development in the Zebrafish Heart

Journal of Cardiovascular Development and Disease, 2021
Proper development and function of the vertebrate heart is vital for embryonic and postnatal life. Many congenital heart defects in humans are associated with disruption of genes that direct the formation or maintenance of atrial and pacemaker ...
Kendall E. Martin, J. Waxman
semanticscholar   +1 more source

Electron-conformational transformations in nanoscopic RyR channels govern both the heart's contraction and beating [PDF]

, 2011
We show that a simple biophysically based electron-conformational model of RyR channel is able to explain and describe on equal footing the oscillatory regime of the heart's cell release unit both in sinoatrial node (pacemaker) cells under normal ...
Markhasin, V. S., Moskvin, A. S., Ryvkin, A. M., Solovyova, O. E.   +3 more
core   +3 more sources

The mind body problem, part three: ascension of sexual function to cerebral level [PDF]

, 2016
Physiologically, the somatic nervous system intervenes in external interaction between the body and environment, while autonomic nervous system ensures the functioning of internal organs.
Motofei, Ion G., Rowland, David L.
core   +3 more sources