Results 31 to 40 of about 58,493 (121)

Sinoatrial nodal disease presenting with tachy-bradycardia syndrome in a fetus of anti-SSA/SSB-positive mother

open access: yesAnnals of Pediatric Cardiology, 2022
Tachy-bradycardia syndrome (TBS) has been reported rarely in the fetus. We present here an unusual dominant involvement of sinoatrial node in a fetus presenting with TBS of anti-Sjögren'syndrome-related antigen A (SS-A) and antigen B (SS-B ...
Balaganesh Karmegaraj
doaj   +1 more source

Generation of a human embryonic stem cell line (WAe009-A-78) carrying homozygous TBX18 knockout

open access: yesStem Cell Research, 2022
T-Box Transcription Factor 18 is a member of the T-box family, encoding TBX18 protein. As a transcriptional repressor, it related to developmental processes of a majority of tissues and organs and plays crucial part in the embryonic development of ...
Qi Xu   +5 more
doaj  

A case report of sinoatrial arrest caused by temporal lobe epilepsy in subclinical glioblastoma

open access: yesBMC Cardiovascular Disorders, 2020
Background Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation.
Jörg Reifart   +4 more
doaj   +1 more source

Atrial and Sinoatrial Node Development in the Zebrafish Heart

open access: yesJournal of Cardiovascular Development and Disease, 2021
Proper development and function of the vertebrate heart is vital for embryonic and postnatal life. Many congenital heart defects in humans are associated with disruption of genes that direct the formation or maintenance of atrial and pacemaker ...
Kendall E. Martin, Joshua S. Waxman
doaj   +1 more source

Pathophysiological Significance of T-type Ca2+ Channels: Properties and Functional Roles of T-type Ca2+ Channels in Cardiac Pacemaking

open access: yesJournal of Pharmacological Sciences, 2005
Calcium channels are essential for excitation-contraction coupling and pacemaker activity in cardiac myocytes. While L-type Ca2+ channels (LCC) have been extensively studied, functional roles of T-type channels (TCC) in native cardiac myocytes are still ...
Kyoichi Ono, Toshihiko Iijima
doaj  

CaMKII in sinoatrial node physiology and dysfunction

open access: yesFrontiers in Pharmacology, 2014
The calcium and calmodulin dependent protein kinase II (CaMKII) is present in sinoatrial node (SAN) pacemaker cells and is required for physiological fight or flight SAN beating rate responses.
Yuejin eWu   +2 more
doaj   +1 more source

Metabolic syndrome remodels electrical activity of the sinoatrial node and produces arrhythmias in rats. [PDF]

open access: yesPLoS ONE, 2013
In the last ten years, the incidences of metabolic syndrome and supraventricular arrhythmias have greatly increased. The metabolic syndrome is a cluster of alterations, which include obesity, hypertension, hypertriglyceridemia, glucose intolerance and ...
Alondra Albarado-Ibañez   +4 more
doaj   +1 more source

Value of peripheral nodes in controlling multilayer networks [PDF]

open access: yesPhys. Rev. E 93, 012309 (2016), 2015
We analyze the controllability of a two-layer network, where driver nodes can be chosen randomly only from one layer. Each layer contains a scale-free network with directed links and the node dynamics depends on the incoming links from other nodes.
arxiv   +1 more source

Acute Isolation of Cells from Murine Sino-atrial Node

open access: yesBio-Protocol, 2020
The cardiac conduction system allows the synchronized propagation of electrical activity through heart muscle. This is initiated by the spontaneous activity of the specialized pacemaker cells of the sino-atrial node (SAN).
Qadeer Aziz   +2 more
doaj   +1 more source

Limit Cycle Oscillations in Pacemaker Cells [PDF]

open access: yesarXiv, 1999
In recent decades, several mathematical models describing the pacemaker activity of the rabbit sinoatrial node have been developed. We demonstrate that it is not possible to establish the existence, uniqueness, and stability of a limit cycle oscillation in those models. Instead we observe an infinite number of limit cycles.
arxiv  

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