Digital Technologies in Providing Development of Algorithms Surgical Treatment of Supraventricular Arrhythmias [PDF]
The aim of the study was the development and clinical application of patient selection algorithm for surgical treatment of longlasting persistent atrial fibrillation. The study included 235 patients with acquired heart disease and coronary artery disease,
Melo+24 more
core +3 more sources
Pathophysiology of Cav1.3 L-type calcium channels in the heart
Ca2+ plays a crucial role in excitation-contraction coupling in cardiac myocytes. Dysfunctional Ca2+ regulation alters the force of contraction and causes cardiac arrhythmias. Ca2+ entry into cardiomyocytes is mediated mainly through L-type Ca2+ channels,
Sahil Zaveri+10 more
doaj +1 more source
Primary structure and functional expression of a cyclic nucleotidegated channel from rabbit aorta [PDF]
Sequences specific for cyclic nucleotide-gated channels (CNG channels) have been amplified by PCR from cDNA of heart, aorta, sinoatrial node, cerebellum, C-cells and kidney.
Ahmad+27 more
core +1 more source
Effects of Cardiac Structural Remodelling During Heart Failure on Cardiac Excitation – Insights from a Heterogeneous 3D Model of the Rabbit Atria [PDF]
Heart failure is a leading cause of morbidity and mortality in the western world. One of the effects of heart failure is the structural remodelling of cardiac tissue, including tissue dilation and development of fibrosis.
Boyett, Mark+7 more
core +2 more sources
Parametric analysis of the ionic concentrations effects in the behavior of the sinoatrial node
A sensibility study on the effect of ionic concentrations in the behavior of the sinoatrial node was carried out. The study was based on the model proposed by H. Zhang, A. V. Holden and M.R. Boyett.
Daniel Alfonso Sierra+2 more
doaj +1 more source
ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function
Supplemental Digital Content is available in the text. Rationale: Cardiac pacemaker cells (PCs) in the sinoatrial node (SAN) have a distinct gene expression program that allows them to fire automatically and initiate the heartbeat.
Giselle Galang+14 more
semanticscholar +1 more source
The effect of gag reflex on cardiac sympatovagal tone [PDF]
Objectives: Heart velocity may be influenced by gagging. The medulla oblongata receives the afferents of gag reflex. Neuronal pools of vomiting, salivation and cardiac parasympathetic fibers are very close in this area.
Jamshir, M.+2 more
core +2 more sources
The rhythmic electrical activity of the heart’s natural pacemaker, the sinoatrial node (SAN), determines cardiac beating rate (BR). SAN electrical activity is tightly controlled by multiple factors, including tissue stretch, which may contribute to ...
L. Katsnelson+8 more
semanticscholar +1 more source
Role of indole derivative SS-68 in increasing the frequency range of cardiac rhythm control (reflex stimulation of the sinoatrial node) [PDF]
Introduction: Cardiac pacing is indicated for sick sinus syndrome. It is performed with a pacemaker via electrodes implanted in the heart. This technique has several disadvantages. The search for alternative methods of cardiac pacing is underway.
Pavel A. Galenko-Yaroshevsky+13 more
doaj +3 more sources
A new algorithm to diagnose atrial ectopic origin from multi lead ECG systems - insights from 3D virtual human atria and torso [PDF]
Rapid atrial arrhythmias such as atrial fibrillation (AF) predispose to ventricular arrhythmias, sudden cardiac death and stroke. Identifying the origin of atrial ectopic activity from the electrocardiogram (ECG) can help to diagnose the early onset of ...
Alday, Erick A. Perez+7 more
core +2 more sources