Results 81 to 90 of about 11,359 (232)

An integrated platform for 2‐D and 3‐D optical and electrical mapping of arrhythmias in Langendorff‐perfused rabbit hearts

The Journal of Physiology, EarlyView.
Abstract figure legend Integrated multimodal platform for panoramic cardiac mapping in isolated heart experiments. On the left, an image of the experimental setup during data acquisition showing a Langendorff‐perfused rabbit heart surrounded by three optical cameras (CAM A, B and C) positioned 120° apart, each coupled with high‐power LEDs for panoramic
Jimena Siles, Vinícius Silva, Tainan Neves, Italo Sandoval, Angélica Quadros, Giovanni Weber, Óscar Barquero, Ilija Uzelac, João Salinet   +8 more
wiley   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Transcriptional profile of the rat cardiovascular system at single-cell resolution

Cell Reports
Summary: We sought to characterize cellular composition across the cardiovascular system of the healthy Wistar rat, an important model in preclinical cardiovascular research.
Alessandro Arduini, Stephen J. Fleming, Ling Xiao, Amelia W. Hall, Amer-Denis Akkad, Mark D. Chaffin, Kayla J. Bendinelli, Nathan R. Tucker, Irinna Papangeli, Helene Mantineo, Patricio Flores-Bringas, Mehrtash Babadi, Christian M. Stegmann, Guillermo García-Cardeña, Mark E. Lindsay, Carla Klattenhoff, Patrick T. Ellinor   +16 more
doaj   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Malignant Anomalous Aortic Origin of the Left Main Coronary Artery Managed by Ostial Reimplantation: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Anomalous origin of the left main coronary artery (LMCA) from the right coronary sinus with an interarterial course is a rare congenital variant associated with a high risk of myocardial ischemia and sudden cardiac death. We describe a 39‐year‐old man presenting with exertional chest pressure and dyspnea whose coronary CT angiography revealed ...
Biruk T. Mengistie, Chernet T. Mengistie, Asteway M. Haile, Nahom D. Gerer, Samuel Mesfin Girma, Elezer B. Zewde   +5 more
wiley   +1 more source

Rhythm Generating Mechanisms in Rat Sinoatrial Node

Current Medical Issues
Background: The major membrane currents responsible for sinoatrial (SA) rhythm generation are generally studied in isolated cardiac cells using electrophysiological tools. Such studies are resource and labor-intensive.
Jesi Charles, Latha Nedumaran, Swetha Raman, Elizabeth Vinod, Rajalakshmi Rajasegaran, Kamalakannan Vadivel, Anand Bhaskar, Sathya Subramani   +7 more
doaj   +1 more source

Rare Case of Rapidly Worsening REM Sleep Induced Bradycardia

Case Reports in Cardiology, 2015
Sinoatrial arrest also known as sinus pause occurs when sinoatrial node of the heart transiently ceases to generate the electrical impulse necessary for the myocardium to contract. It may last from 2.0 seconds to several minutes. Etiologies of sinoatrial
Ayyappa S. Duba, Suneetha Jasty, Ankit Mahajan, Vijay Kodadhala, Raza Khan, Prithviraj Rai, Mohammad Ghazvini   +6 more
doaj   +1 more source

Phase response characteristics of sinoatrial node cells

Computers in Biology and Medicine, 2007
In this work, the dynamic response of the sinoatrial node (SAN), the natural pacemaker of the heart, to short external stimuli is investigated using the Zhang et al. model. The model equations are solved twice for the central cell and for the peripheral cell.
Tsalikakis, D. G., Zhang, H. G., Fotiadis, D. I., Kremmydas, G. P., Michalis, L. K.   +4 more
openaire   +4 more sources

Magnesium Sulfate Combination Therapy for Aconitine‐Induced Electrical Storm

Annals of Noninvasive Electrocardiology, Volume 30, Issue 6, November 2025.
Treatment course of 28 episodes of electrical storm caused by aconitine poisoning with combined magnesium sulfate therapy. ABSTRACT We present the case of a 74‐year‐old man who developed 28 episodes of electrical storm secondary to aconitine poisoning from homemade herbal wine consumption, followed by complete recovery through 28 electrical ...
Liujiang Ran, Jun Si, Yanyan Liu
wiley   +1 more source

Simplified 2D Bidomain Model of Whole Heart Electrical Activity and ECG Generation

Measurement Science Review, 2014
The aim of this study was the development of a geometrically simple and highly computationally-efficient two dimensional (2D) biophysical model of whole heart electrical activity, incorporating spontaneous activation of the sinoatrial node (SAN), the ...
Sovilj Siniša, Magjarević Ratko, Abed Amr Al, Lovell Nigel H., Dokos Socrates   +4 more
doaj   +1 more source