Results 81 to 90 of about 1,311,541 (283)

Sphingosine‐1‐Phosphate Receptor Modulators for the Treatment of Ulcerative Colitis: A Narrative Review Focusing on Safety

United European Gastroenterology Journal, EarlyView.
ABSTRACT Ulcerative colitis is a chronic immune‐mediated inflammatory disease of the colon that causes considerable morbidity and increases the risk of colorectal cancer. Several targeted therapies have been developed for moderate‐to‐severe ulcerative colitis, significantly improving its management.
Massimo C. Fantini, Diego Centonze, Giovanni Giacobazzi, Silvia Benemei, Emanuele Romeo   +4 more
wiley   +1 more source

Computer Three-Dimensional Reconstruction of the Sinoatrial Node [PDF]

Circulation, 2005
Background— There is an effort to build an anatomically and biophysically detailed virtual heart, and, although there are models for the atria and ventricles, there is no model for the sinoatrial node (SAN).
Dobrzynski, H., Li, J., Tellez, J., Greener, I. D., Nikolski, V. P., Wright, S. E., Parson, S. H., Jones, S. A., Lancaster, M. K., Yamamoto, M., Honjo, H., Takagishi, Y., Kodama, I., Efimov, I. R., Billeter, R., Boyett, M. R.   +15 more
openaire   +3 more sources

Heart rate variability in horses with and without severe equine asthma

Equine Veterinary Journal, Volume 57, Issue 3, Page 611-618, May 2025.
Abstract Background Equine asthma in severe form (severe equine asthma [sEA]) shares remarkable similarities with human asthma. Human studies detected changes in the autonomic nervous system function in asthmatic patients based on heart rate variability (HRV) analysis. Study design Observational study. Objectives To investigate the relationship between
Zsófia Nyerges‐Bohák, Levente Kovács, Ágnes Povázsai, Enikő Hamar, Péter Póti, Márta Ladányi   +5 more
wiley   +1 more source

Molecular Pathway for the Localized Formation of the Sinoatrial Node [PDF]

Circulation Research, 2007
The sinoatrial node, which resides at the junction of the right atrium and the superior caval vein, contains specialized myocardial cells that initiate the heart beat. Despite this fundamental role in heart function, the embryonic origin and mechanisms of localized formation of the sinoatrial node have not been defined.
Mommersteeg, M, Hoogaars, WM, Prall, O, de Gier-de Vries, C, Wiese, C, Clout, D, Papaioannou, V, Brown, N, Harvey, R, Moorman, A, Christoffels, V   +10 more
openaire   +3 more sources

A case report of sinoatrial arrest caused by temporal lobe epilepsy in subclinical glioblastoma

BMC Cardiovascular Disorders, 2020
Background Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation.
Jörg Reifart, Marlene Tschernatsch, Christian W. Hamm, Johannes Sperzel, Andreas Hain   +4 more
doaj   +1 more source

Nkx2-5 defines a subpopulation of pacemaker cells and is essential for the physiological function of the sinoatrial node in mice

Development, 2019
The sinoatrial node (SAN), the primary cardiac pacemaker, consists of a head domain and a junction/tail domain that exhibit different functional properties. However, the underlying molecular mechanism defining these two pacemaker domains remains elusive.
Hua Li, Dainan Li, Yuzhi Wang, Zhen Huang, Jue Xu, Tianfang Yang, Linyan Wang, Q. Tang, C. Cai, Hai Huang, Yanding Zhang, YiPing Chen   +11 more
semanticscholar   +1 more source

Volume kinetics of lactated Ringer's solution in adult horses

Equine Veterinary Journal, EarlyView.
Abstract Background Fluid therapy in horses is primarily empirical. Evidence‐based quantification of the disposition of intravenous (IV) crystalloids used in clinical practice could enhance the effectiveness of fluid therapy. Objectives To determine the pharmacokinetics (i.e., volume kinetics: VK) and associated haemodynamic effects of IV lactated ...
William W. Muir, Xiu Ting Yiew, Shane W. Bateman, Robert G. Hahn   +3 more
wiley   +1 more source

Cell-based Biological Pacemakers: Progress and Problems [PDF]

, 2018
The number of permanent pacemaker implantations has been increasing due to the aging of populations worldwide and the increase in the numbers of patients with heart diseases.
Ito, Hiroshi, Nakamura, Kazufumi, Saito, Yukihiro   +2 more
core   +1 more source

The clinical effect of an implanted vagus nerve stimulator in a patient with chronic cluster headache and focal epilepsy – A case report

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Treatment for chronic cluster headache (CCH) is often insufficient. Non‐invasive vagus nerve stimulation (nVNS) was shown to be effective as acute treatment in episodic cluster headache (ECH) and open‐label studies have shown a potential effect in CCH.
Paulien J. van Tilborg, Anemoon T. Bosch, Roland D. Thijs, Rolf Fronczek   +3 more
wiley   +1 more source

The morphologic development of the sinoatrial node in the mouse

The American Journal of Cardiology, 1970
Abstract A plastic embedding technique was employed on mouse embryos after fixation with a gluteraldehyde-paraformaldehyde mixture and preparation of large, 1 to 2 μ sections cut on a rotary microtome with steel knives. It was then possible to trace the sinoatrial node back to mouse embryos of 4 sol1 2 mm crown-rump length ( 10 1 2 days
Departments of Pediatrics (Cardiology) and Pathology, University of Florida College of Medicine, Gainesville, Fla. 32601 USA ( host institution ), Van Mierop, L.H.S., Gessner, Ira H.   +2 more
openaire   +4 more sources