Results 81 to 90 of about 1,344,270 (316)

ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION [PDF]

, 2018
Abnormalities in cardiac stress signaling underlie a number of cardiovascular diseases (e.g. arrhythmias and heart failure). Cardiac stress signaling pathways normally integrate signals from the sympathetic nervous system to promote efficient contraction
Baldwin, Tanya A., Baldwin, Tanya A.
core   +1 more source

Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review) [PDF]

, 2017
Sick sinus syndrome (SSS) encompasses a group of disorders whereby the heart is unable to perform its pacemaker function, due to genetic and acquired causes.
Chan, C, Chan, Y, Keung, W, Laxton, V, Li, K, Li, R, Liu, T, Tse, G, Wong, A   +8 more
core   +2 more sources

Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues

Small Methods, EarlyView.
This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley   +1 more source

Systolic‐dominant coronary flow in rats and mice: Challenging the diastolic paradigm across conscious and anaesthetized states

Experimental Physiology, EarlyView.
Abstract Extensive research in humans, dogs, rabbits, rats, mice and other mammals has consistently demonstrated that coronary blood flow (CBF) peaks during ventricular diastole. For example, studies using transthoracic Doppler echocardiography in anaesthetized rats and mice, isolated blood‐perfused rat hearts and Doppler probes sutured to the ...
Heidi L. Lujan, Theodore W. Kurtz, Stephen E. DiCarlo   +2 more
wiley   +1 more source

A new algorithm to diagnose atrial ectopic origin from multi lead ECG systems - insights from 3D virtual human atria and torso [PDF]

, 2015
Rapid atrial arrhythmias such as atrial fibrillation (AF) predispose to ventricular arrhythmias, sudden cardiac death and stroke. Identifying the origin of atrial ectopic activity from the electrocardiogram (ECG) can help to diagnose the early onset of ...
Alday, Erick A. Perez, Butters, Timothy D., Colman, Michael A., Hancox, Jules C., Higham, Jonathan, Langley, Philip, Workman, Antony J., Zhang, Henggui   +7 more
core   +2 more sources

The morphologic development of the sinoatrial node in the mouse

The American Journal of Cardiology, 1970
Abstract A plastic embedding technique was employed on mouse embryos after fixation with a gluteraldehyde-paraformaldehyde mixture and preparation of large, 1 to 2 μ sections cut on a rotary microtome with steel knives. It was then possible to trace the sinoatrial node back to mouse embryos of 4 sol1 2 mm crown-rump length ( 10 1 2 days
Departments of Pediatrics (Cardiology) and Pathology, University of Florida College of Medicine, Gainesville, Fla. 32601 USA ( host institution ), Van Mierop, L.H.S., Gessner, Ira H.   +2 more
openaire   +3 more sources

Atrial fibrillation, sinoatrial and atrioventricular node dysfunction in a mouse model of heart failure with preserved ejection fraction

Experimental Physiology, EarlyView.
Summary of the timeline of characterized events related to atrial fibrilation (AF) and diastolic dysfunction in a mouse heart failure with preserved ejection fraction (HFpEF) model. Three weeks after the initiation of the diet regimen with high fat diet (HFD) and Nω‐nitro‐l‐arginine methyl ester (l‐NAME) in drinking water to induce HFpEF, significantly
Bernadin Ndongson‐Dongmo, Reinhard Bauer, Finn Olav Levy   +2 more
wiley   +1 more source

A case report of sinoatrial arrest caused by temporal lobe epilepsy in subclinical glioblastoma

BMC Cardiovascular Disorders, 2020
Background Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation.
Jörg Reifart, Marlene Tschernatsch, Christian W. Hamm, Johannes Sperzel, Andreas Hain   +4 more
doaj   +1 more source

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program

Development, 2019
The rate of contraction of the heart relies on proper development and function of the sinoatrial node, which consists of a small heterogeneous cell population, including Tbx3+ pacemaker cells. Here, we have isolated and characterized the Tbx3+ cells from
Vincent W. W. van Eif, Sonia Stefanovic, K. van Duijvenboden, Martijn l. Bakker, Vincent Wakker, C. de Gier-de Vries, S. Zaffran, A. Verkerk, B. Boukens, V. Christoffels   +9 more
semanticscholar   +1 more source

Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits

Experimental Physiology, EarlyView.
Abstract Glycogen storage disease III (GSD‐III) is caused by an inherited deficiency of the glycogen debranching enzyme. Affecting the liver, muscle and heart, GSD‐IIIa is the most common GSD‐III subtype. We evaluated the feasibility and safety of a physical exercise intervention in patients with GSD‐IIIa and its effects at the multisystem level.
Asunción Bustos‐Sellers, Almudena Montalvo‐Pérez, Araceli Boraita, Gonzalo Saco‐Ledo, Lidia B. Alejo, David Barranco‐Gil, Pedro L. Valenzuela, Nerea López‐Maldonado, Roser Ferrer‐Costa, Javier Esparcia‐Estrela, Celia Monteagudo‐López, Tomàs Pinós, Alejando Santos‐Lozano, Alejandro Lucia, Alfredo Santalla   +14 more
wiley   +1 more source