Results 91 to 100 of about 55,525 (134)

Loss of Natriuretic Peptide Receptor C Enhances Sinoatrial Node Dysfunction in Aging and Frail Mice. [PDF]

J Gerontol A Biol Sci Med Sci, 2022
Jansen HJ, Moghtadaei M, Rafferty SA, Belke DD, Rose RA.   +4 more
europepmc   +1 more source

SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmias

EMBO Molecular Medicine, 2017
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a stress‐provoked ventricular arrhythmia, which also manifests sinoatrial node (SAN) dysfunction.
Shiraz Haron‐Khun, David Weisbrod, Hanna Bueno, Dor Yadin, Joachim Behar, Asher Peretz, Ofer Binah, Edith Hochhauser, Michael Eldar, Yael Yaniv, Michael Arad, Bernard Attali   +11 more
doaj   +1 more source

Pharmacologic Approach to Sinoatrial Node Dysfunction. [PDF]

Annu Rev Pharmacol Toxicol, 2021
Mesirca P, Fedorov VV, Hund TJ, Torrente AG, Bidaud I, Mohler PJ, Mangoni ME.   +6 more
europepmc   +1 more source

Artificial Cardiac Conduction System: Simulating Heart Function for Advanced Computational Problem Solving [PDF]

arXiv
This work proposes a novel bio-inspired metaheuristic called Artificial Cardiac Conduction System (ACCS) inspired by the human cardiac conduction system. The ACCS algorithm imitates the functional behaviour of the human heart that generates and sends signals to the heart muscle, initiating it to contract.
arxiv  

Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction

Scientific Reports, 2017
Adenylyl cyclase type 9 (AC9) is found tightly associated with the scaffolding protein Yotiao and the IKs ion channel in heart. But apart from potential IKs regulation, physiological roles for AC9 are unknown.
Yong Li, Tanya A. Baldwin, Yan Wang, Janani Subramaniam, Anibal Garza Carbajal, Cameron S. Brand, Shane R. Cunha, Carmen W. Dessauer   +7 more
doaj   +1 more source

Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

Stem Cells International, 2019
Background. Tbx18 is a vital transcription factor involved in embryonic sinoatrial node (SAN) formation process but is gradually vanished after birth.
Yannan Hu, Ning Li, Liang Liu, Hao Zhang, Xiang Xue, Xin Shao, Yu Zhang, Xilong Lang   +7 more
doaj   +1 more source

Medical Management of Hemodynamically Unstable Sinoatrial Node Dysfunction in a Patient With Intracardiac Lymphoma. [PDF]

JACC CardioOncol, 2021
Martz CA, Jarbeau JF, Castillo JJ, Fisher DC, Nohria A.   +4 more
europepmc   +1 more source

Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve [PDF]

arXiv, 2019
Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart valves. This leads to risks of valve leaflet dysfunction, a life threatening event.
arxiv  

Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway. [PDF]

Evid Based Complement Alternat Med, 2021
Zhang H, Hao M, Li L, Chen K, Qi J, Chen W, Cai X, Chen C, Liu Z, Hou P.   +9 more
europepmc   +1 more source

Dual network structure of the AV node [PDF]

arXiv
Biological systems, particularly the brain, are frequently analyzed as networks, conveying mechanistic insights into their function and pathophysiology. This is the first study of a functional network of cardiac tissue. We use calcium imaging to obtain two functional networks in a subsidiary but essential pacemaker of the heart, the atrioventricular ...
arxiv