Results 91 to 100 of about 68,194 (193)

Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity

open access: yesFrontiers in Cardiovascular Medicine, 2021
The understanding of the electrophysiological mechanisms that underlie mechanosensitivity of the sinoatrial node (SAN), the primary pacemaker of the heart, has been evolving over the past century.
Daniel Turner   +6 more
doaj   +1 more source

Cardiac output‐mediated regulation of cerebral blood flow during exercise: Clinical perspectives on the indirect impact of muscle metaboreflex

open access: yesExperimental Physiology, EarlyView.
Abstract The muscle metaboreflex stimulates the elevation of arterial blood pressure, aiming to rectify the oxygen deficit by enhancing oxygen delivery to support muscle activity. Moreover, activating the muscle metaboreflex significantly increases cardiac output (CO) by increasing factors such as heart rate, ventricular contractility, preload, stroke ...
Shigehiko Ogoh
wiley   +1 more source

Electrophysiological effects of diltiazem in chronic bifascicular block

open access: yesJournal of Medical and Scientific Research, 2017
Background: Literature on diltiazem in intraventricular conduction defects is meagre. We studied effects and safety of diltiazem in chronic bifascicular block using His-bundle electrocardiography and pacing.
Ajaz A, Khalid Mohiud, Syed Manzoor
doaj   +1 more source

An explainable artificial intelligence approach for predicting cardiovascular outcomes using electronic health records.

open access: yesPLOS Digital Health, 2022
Understanding the conditionally-dependent clinical variables that drive cardiovascular health outcomes is a major challenge for precision medicine.
Sergiusz Wesołowski   +14 more
doaj   +1 more source

Unravelling early sinus node dysfunction after paediatric cardiac surgery: a pre-existing arrhythmogenic substrate

open access: yesInteractive Cardiovascular and Thoracic Surgery, 2022
Early postoperative sinus node dysfunction (SND) is common in paediatric patients undergoing surgical correction of congenital heart disease (CHD). At present, the pathophysiology of these arrhythmias is incompletely understood.
N. R. Ramdat Misier   +7 more
semanticscholar   +1 more source

Hemodynamics of a Bileaflet Mechanical Heart Valve with Different Levels of Dysfunction [PDF]

open access: yesVolume 2 Issue 5 - 2017, 2017
Heart disease is one of leading causes of mortality worldwide. Healthy heart valves are key for proper heart function. When these valves dysfunction, a replacement is often necessary in severe cases. The current study presents an investigation of the pulsatile blood flow through a bileaflet mechanical heart valve (BMHV) where one leaflet is healthy and
arxiv   +1 more source

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder   +4 more
wiley   +1 more source

DBGDGM: Dynamic Brain Graph Deep Generative Model [PDF]

open access: yesarXiv, 2023
Graphs are a natural representation of brain activity derived from functional magnetic imaging (fMRI) data. It is well known that clusters of anatomical brain regions, known as functional connectivity networks (FCNs), encode temporal relationships which can serve as useful biomarkers for understanding brain function and dysfunction.
arxiv  

Heart rate variability in horses with and without severe equine asthma

open access: yesEquine Veterinary Journal, Volume 57, Issue 3, Page 611-618, May 2025.
Abstract Background Equine asthma in severe form (severe equine asthma [sEA]) shares remarkable similarities with human asthma. Human studies detected changes in the autonomic nervous system function in asthmatic patients based on heart rate variability (HRV) analysis. Study design Observational study. Objectives To investigate the relationship between
Zsófia Nyerges‐Bohák   +5 more
wiley   +1 more source

Temporary neonatal atrial pacing through the umbilical venous route: A novel technique

open access: yesAnnals of Pediatric Cardiology, 2011
Atrial pacing in the neonate is rarely done due to constraints of equipment, technical knowhow, and risk of complications. We describe a novel method of atrial pacing in the new born using equipment readily available in any intensive care unit.
Hiren N Doshi, Seema T Lokare
doaj   +1 more source

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