Results 21 to 30 of about 10,441 (208)

Sinoatrial node dysfunction induces cardiac arrhythmias in diabetic mice. [PDF]

Cardiovasc Diabetol, 2014
The aim of this study was to probe cardiac complications, including heart-rate control, in a mouse model of type-2 diabetes. Heart-rate development in diabetic patients is not straight forward: In general, patients with diabetes have faster heart rates compared to non-diabetic individuals, yet diabetic patients are frequently found among patients ...
Soltysinska E, Speerschneider T, Winther SV, Thomsen MB.   +3 more
europepmc   +5 more sources

Junctional Pacemaker May Replace the Sinoatrial Node

Cardiovascular Innovations and Applications, 2021
Junctional rhythm is usually seen in the clinic with different causes. We report a case of bicuspid aortic valve accompanied by sinoatrial node dysfunction.
Min Lin, Yuqin Xiong, Yipin Lin, Yuhua Li, Lijuan Zhang   +4 more
doaj   +1 more source

Cycle length restitution in sinoatrial node cells: a theory for understanding spontaneous action potential dynamics. [PDF]

PLoS ONE, 2014
Normal heart rhythm (sinus rhythm) is governed by the sinoatrial node, a specialized and highly heterogeneous collection of spontaneously active myocytes in the right atrium.
Patric Glynn, Birce Onal, Thomas J Hund
doaj   +1 more source

Are physiological oscillations physiological?

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Digital Technologies in Providing Development of Algorithms Surgical Treatment of Supraventricular Arrhythmias [PDF]

, 2006
The aim of the study was the development and clinical application of patient selection algorithm for surgical treatment of longlasting persistent atrial fibrillation. The study included 235 patients with acquired heart disease and coronary artery disease,
Melo, Benussi, Chang, Fareh, Elvan, Gomes, Lee, Peretto, Saksena, Teh, Nemkov, Je, Evtushenko, Pasic, Saksena, Yeh, Nath, Evtushenko, Evtushenko, Evtushenko, Swanson, La Meir, Saliba, Wenning, Nasso   +24 more
core   +3 more sources

Pathophysiology of Cav1.3 L-type calcium channels in the heart

Frontiers in Physiology, 2023
Ca2+ plays a crucial role in excitation-contraction coupling in cardiac myocytes. Dysfunctional Ca2+ regulation alters the force of contraction and causes cardiac arrhythmias. Ca2+ entry into cardiomyocytes is mediated mainly through L-type Ca2+ channels,
Sahil Zaveri, Sahil Zaveri, Ujala Srivastava, Yongxia Sarah Qu, Yongxia Sarah Qu, Yongxia Sarah Qu, Mohamed Chahine, Mohamed Chahine, Mohamed Boutjdir, Mohamed Boutjdir, Mohamed Boutjdir   +10 more
doaj   +1 more source

Temporal Characteristics and Management of Prolonged Sinus Pause Following Atrial Fibrillation Termination After Catheter Ablation-A Preliminary Study. [PDF]

Ann Noninvasive Electrocardiol
Twelve of the 1330 patients who underwent AF catheter ablation showed PSP ≥ 3 s after AF termination post ablation. The temporal characteristics of PSP were described. Nine of the 12 patients had no need for permanent pacing. We concluded that a ‘watch‐and‐wait’ strategy could be adopted in these patients.
Guo Y, Cai C, Chen H, Gu K, Ju W, Yang G, Shi J, Wang Z, Liu H, Jiang X, Cui C, Li M, Chen M.   +12 more
europepmc   +2 more sources

Aging and Sinoatrial Node Dysfunction [PDF]

Circulation, 2007
In the century since the discovery by Keith and Flack of the sinoatrial node in the mole heart, a detailed mosaic of its cellular, anatomic, and electrophysiological properties has emerged. The human sinus node has been found to be anatomically constant and well localized, occupying an approximately 10-mm subepicardial region on the sulcus terminalis ...
Haris M. Haqqani, Jonathan M. Kalman
openaire   +1 more source

Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review) [PDF]

, 2017
Sick sinus syndrome (SSS) encompasses a group of disorders whereby the heart is unable to perform its pacemaker function, due to genetic and acquired causes.
Chan, C, Chan, Y, Keung, W, Laxton, V, Li, K, Li, R, Liu, T, Tse, G, Wong, A   +8 more
core   +8 more sources

RyR2(R4496C) Expression Induces Sinoatrial Node Dysfunction [PDF]

Biophysical Journal, 2011
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is an arrhythmogenic disease characterized by stress-triggered syncope and sudden death. While ventricular tachycardia appears only during stress conditions, CPVT patients manifest basal sino-atrial node (SAN) dysfunction, but the underlying mechanism remains unknown.
Neco, Patricia, Torrente, Angelo, Zorio, Esther, Priori, Silvia G., Richard, Sylvain, Benitah, Jean-Pierre, Mangoni, Matteo, Gomez, Ana M.   +7 more
openaire   +1 more source