Junctional Pacemaker May Replace the Sinoatrial Node
Cardiovascular Innovations and Applications, 2021 Junctional rhythm is usually seen in the clinic with different causes. We report a case of bicuspid aortic valve accompanied by sinoatrial node dysfunction.
Min Lin +4 more
doaj +1 more source
Cycle length restitution in sinoatrial node cells: a theory for understanding spontaneous action potential dynamics. [PDF]
PLoS ONE, 2014 Normal heart rhythm (sinus rhythm) is governed by the sinoatrial node, a specialized and highly heterogeneous collection of spontaneously active myocytes in the right atrium.
Patric Glynn, Birce Onal, Thomas J Hund
doaj +1 more source
Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review) [PDF]
, 2017 Sick sinus syndrome (SSS) encompasses a group of disorders whereby the heart is unable to perform its pacemaker function, due to genetic and acquired causes.
Chan, C +8 more
core +10 more sources
Pathophysiology of Cav1.3 L-type calcium channels in the heart
Frontiers in Physiology, 2023 Ca2+ plays a crucial role in excitation-contraction coupling in cardiac myocytes. Dysfunctional Ca2+ regulation alters the force of contraction and causes cardiac arrhythmias. Ca2+ entry into cardiomyocytes is mediated mainly through L-type Ca2+ channels,
Sahil Zaveri +10 more
doaj +1 more source
Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases [PDF]
, 2020 Aims The genetic cause of cardiac conduction system disease (CCSD) has not been fully elucidated. Whole-exome sequencing (WES) can detect various genetic variants; however, the identification of pathogenic variants remains a challenge.
Asano, Yoshihiro +44 more
core +1 more source
Digital Technologies in Providing Development of Algorithms Surgical Treatment of Supraventricular Arrhythmias [PDF]
, 2006 The aim of the study was the development and clinical application of patient selection algorithm for surgical treatment of longlasting persistent atrial fibrillation. The study included 235 patients with acquired heart disease and coronary artery disease,
Melo +24 more
core +3 more sources
RyR2(R4496C) Expression Induces Sinoatrial Node Dysfunction [PDF]
Biophysical Journal, 2011 Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is an arrhythmogenic disease characterized by stress-triggered syncope and sudden death. While ventricular tachycardia appears only during stress conditions, CPVT patients manifest basal sino-atrial node (SAN) dysfunction, but the underlying mechanism remains unknown.
Neco, Patricia +7 more
openaire +1 more source
A Case of Complete AV Blockade in Patient with Lyme Borreliosis
Архивъ внутренней медицины, 2022 Lyme disease (tick-borne borreliosis) is an infectious vector-borne natural focal disease that tends to a chronic and recurrent course with a predominant damage to the skin, nervous system, musculoskeletal system and heart. Cardiac features is manifested,
O. N. Denisov +2 more
doaj +1 more source
The mind body problem, part three: ascension of sexual function to cerebral level [PDF]
, 2016 Physiologically, the somatic nervous system intervenes in external interaction between the body and environment, while autonomic nervous system ensures the functioning of internal organs.
Motofei, Ion G., Rowland, David L.
core +3 more sources
Metabolic syndrome remodels electrical activity of the sinoatrial node and produces arrhythmias in rats. [PDF]
PLoS ONE, 2013 In the last ten years, the incidences of metabolic syndrome and supraventricular arrhythmias have greatly increased. The metabolic syndrome is a cluster of alterations, which include obesity, hypertension, hypertriglyceridemia, glucose intolerance and ...
Alondra Albarado-Ibañez +4 more
doaj +1 more source