Results 41 to 50 of about 10,441 (208)
A protective role of Nox1/NADPH oxidase in a mouse model with hypoxia-induced bradycardia
Journal of Pharmacological Sciences, 2015 Although it has been reported that endotoxin-induced expression of Nox1 in the heart contributes to apoptosis in cardiomyocytes, functional role of Nox1 at the physiological expression level has not been elucidated.
Akiteru Kojima +7 more
doaj +1 more source
The Role of Ivabradine in the Management of Angina Pectoris [PDF]
, 2016 Stable angina pectoris affects 2–4 % of the population in Western countries and entails an annual risk of death and nonfatal myocardial infarction of 1–2 % and 3 %, respectively.
De Silva, R, Giavarini, A
core +2 more sources
Familial sinoatrial node dysfunction. Increased vagal tone a possible aetiology. [PDF]
Heart, 1976 Clinical and electrophysiological studies of a 13-year-old boy with sinus bradycardia revealed sinus node dysfunction. Long-term follow-up data of members of his family indicated familial sinus node dysfucntion. Increased vagal tone was present in all patients.
D G, Caralis, P J, Varghese
openaire +2 more sources
Frontiers in Physiology, 2015 The heart’s regular electrical activity is initiated by specialized cardiac pacemaker cells residing in the sinoatrial node. The rate and rhythm of spontaneous action potential firing of sinoatrial node cells are regulated by stochastic mechanisms that ...
Yael eYaniv +2 more
doaj +1 more source
Changes in Ion Channel Gene Expression Underlying Heart Failure-Induced Sinoatrial Node Dysfunction [PDF]
Circulation: Heart Failure, 2011 Background— Heart failure (HF) causes a decline in the function of the pacemaker of the heart—the sinoatrial node (SAN). The aim of the study was to investigate HF-induced changes in the expression of the ion channels and related proteins underlying the pacemaker activity of the SAN.
Yanni Gerges, Joseph +9 more
openaire +2 more sources
Zdorovʹe Rebenka, 2012 In the article there are presented the data about history of development of noninvasive electrophysiological research and its application in pediatrics.
N.V. Nagornaya +2 more
doaj +1 more source
The role of the calcium and the voltage clocks in sinoatrial node dysfunction. [PDF]
Yonsei Med J, 2011 Recent evidence indicates that the voltage clock (cyclic activation and deactivation of membrane ion channels) and Ca(2+) clocks (rhythmic spontaneous sarcoplasmic reticulum Ca(2+) release) jointly regulate sinoatrial node (SAN) automaticity. However, the relative importance of the voltage clock and Ca(2+) clock for pacemaking was not revealed in sick ...
Joung B, Chen PS, Lin SF.
europepmc +4 more sources
The Involvement of TRPC3 channels in Sinoatrial Arrhythmias
Frontiers in Physiology, 2015 Atrial fibrillation (AF) is a significant contributor to cardiovascular morbidity and mortality. The currently available treatments are limited and AF continues to be a major clinical challenge.
Yue-Kun eJu +6 more
doaj +1 more source
Trends in research on sick sinus syndrome: A bibliometric analysis from 2000 to 2022
Frontiers in Cardiovascular Medicine, 2022 Sick sinus syndrome (SSS) is a refractory arrhythmia disease caused by the pathological changes of sinoatrial node and its adjacent tissues. 2,251 publications related to SSS were retrieved from Web of Science database from 2000 to 2022 and analyzed by ...
Xin’ai Zhang +6 more
doaj +1 more source
Российский кардиологический журнал, 2016 Resting heart rate is a strong predictor of mortality and cardiovascular outcome in patients with chronic heart failure. А specific inhibitor of the If current in the sinoatrial node ivabradine improves clinical outcome in patients with heart failure and
S. N. Tereshchenko +2 more
doaj +1 more source