Results 51 to 60 of about 10,498 (222)
Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review) [PDF]
, 2017 Sick sinus syndrome (SSS) encompasses a group of disorders whereby the heart is unable to perform its pacemaker function, due to genetic and acquired causes.
Chan, C +8 more
core +8 more sources
Mitochondrial dysfunction on sinoatrial node and pulmonary vein electrophysiological activities
Experimental and Therapeutic Medicine, 2017 Atrial fibrillation (AF) is associated with mitochondrial dysfunction. Sinoatrial node (SAN) dysfunction increases arrhythmogenesis of pulmonary veins (PVs), which is the most important trigger of AF; however, it is not clear whether mitochondrial dysfunction differentially regulates electrical activity of SANs and PVs.
Yung‐Kuo Lin +7 more
openalex +5 more sources
Congenital Deafness and Sinoatrial Node Dysfunction in Mice Lacking Class D L-Type Ca2+ Channels [PDF]
Cell, 2000 Voltage-gated L-type Ca2+ channels (LTCCs) containing a pore-forming alpha1D subunit (D-LTCCs) are expressed in neurons and neuroendocrine cells. Their relative contribution to total L-type Ca2+ currents and their physiological role and significance as a drug target remain unknown.
Josef Platzer +7 more
openalex +4 more sources
Zdorovʹe Rebenka, 2012 In the article there are presented the data about history of development of noninvasive electrophysiological research and its application in pediatrics.
N.V. Nagornaya +2 more
doaj +1 more source
Trends in research on sick sinus syndrome: A bibliometric analysis from 2000 to 2022
Frontiers in Cardiovascular Medicine, 2022 Sick sinus syndrome (SSS) is a refractory arrhythmia disease caused by the pathological changes of sinoatrial node and its adjacent tissues. 2,251 publications related to SSS were retrieved from Web of Science database from 2000 to 2022 and analyzed by ...
Xin’ai Zhang +6 more
doaj +1 more source
The Role of Ivabradine in the Management of Angina Pectoris [PDF]
, 2016 Stable angina pectoris affects 2–4 % of the population in Western countries and entails an annual risk of death and nonfatal myocardial infarction of 1–2 % and 3 %, respectively.
De Silva, R, Giavarini, A
core +2 more sources
The Involvement of TRPC3 channels in Sinoatrial Arrhythmias
Frontiers in Physiology, 2015 Atrial fibrillation (AF) is a significant contributor to cardiovascular morbidity and mortality. The currently available treatments are limited and AF continues to be a major clinical challenge.
Yue-Kun eJu +6 more
doaj +1 more source
A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart [PDF]
, 1982 These experiments employ the photoisomerizable compound, 3,3'-bis- [alpha-(trimethylammonium)methyl]azobenzene (Bis-Q), to study the response to muscarinic agents in frog myocardium. In homogenates from the heart, trans-Bis-Q blocks the binding of [3H]-N-
Birdsall, Nigel J. M. +5 more
core +1 more source
Российский кардиологический журнал, 2016 Resting heart rate is a strong predictor of mortality and cardiovascular outcome in patients with chronic heart failure. А specific inhibitor of the If current in the sinoatrial node ivabradine improves clinical outcome in patients with heart failure and
S. N. Tereshchenko +2 more
doaj +1 more source