Results 61 to 70 of about 59,209 (214)
A protective role of Nox1/NADPH oxidase in a mouse model with hypoxia-induced bradycardia
Journal of Pharmacological Sciences, 2015 Although it has been reported that endotoxin-induced expression of Nox1 in the heart contributes to apoptosis in cardiomyocytes, functional role of Nox1 at the physiological expression level has not been elucidated.
Akiteru Kojima +7 more
doaj +1 more source
Frontiers in Physiology, 2015 The heart’s regular electrical activity is initiated by specialized cardiac pacemaker cells residing in the sinoatrial node. The rate and rhythm of spontaneous action potential firing of sinoatrial node cells are regulated by stochastic mechanisms that ...
Yael eYaniv +2 more
doaj +1 more source
Emergent networks in fractional percolation [PDF]
, 2021 Real networks are vulnerable to random failures and malicious attacks. However, when a node is harmed or damaged, it may remain partially functional, which helps to maintain the overall network structure and functionality. In this paper, we study the network structure for a fractional percolation process [Shang, Phys. Rev.
arxiv +1 more source
Zdorovʹe Rebenka, 2012 In the article there are presented the data about history of development of noninvasive electrophysiological research and its application in pediatrics.
N.V. Nagornaya +2 more
doaj +1 more source
Trends in research on sick sinus syndrome: A bibliometric analysis from 2000 to 2022
Frontiers in Cardiovascular Medicine, 2022 Sick sinus syndrome (SSS) is a refractory arrhythmia disease caused by the pathological changes of sinoatrial node and its adjacent tissues. 2,251 publications related to SSS were retrieved from Web of Science database from 2000 to 2022 and analyzed by ...
Xin’ai Zhang +6 more
doaj +1 more source
Holter monitoring, sinoatrial conduction time, prognosis [PDF]
, 2013 Background: To evaluate the usefulness of the Holter method of sinoatrial conduction time (SACT) calculation in predicting the future occurrence of sinus node disease, and the emergence of indications for permanent pacing in patients with unexplained ...
Kramarz, Elżbieta, Makowski, Karol
core +2 more sources
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking [PDF]
, 2022 Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are the molecular correlate of the I-f current and are critically involved in controlling neuronal excitability and the autonomous rhythm of the heart.
Biel, Martin +3 more
core +1 more source
Structure of Cell Networks Critically Determines Oscillation Regularity [PDF]
Journal of Theoretical Biology 297, 61-72 (2012), 2011 Biological rhythms are generated by pacemaker organs, such as the heart pacemaker organ (the sinoatrial node) and the master clock of the circadian rhythms (the suprachiasmatic nucleus), which are composed of a network of autonomously oscillatory cells.
arxiv +1 more source
The Involvement of TRPC3 channels in Sinoatrial Arrhythmias
Frontiers in Physiology, 2015 Atrial fibrillation (AF) is a significant contributor to cardiovascular morbidity and mortality. The currently available treatments are limited and AF continues to be a major clinical challenge.
Yue-Kun eJu +6 more
doaj +1 more source
Insulin signaling is critical for sinoatrial node maintenance and function
Experimental and Molecular Medicine, 2023 Insulin and insulin-like growth factor 1 (IGF-1) signaling regulate cellular growth and glucose metabolism in the myocardium. However, their physiological role in the cells of the cardiac conduction system has never been explored. Therefore, we sought to
Sangmi Ock +6 more
doaj +1 more source