Results 81 to 90 of about 10,498 (222)
PLOS Digital Health, 2022 Understanding the conditionally-dependent clinical variables that drive cardiovascular health outcomes is a major challenge for precision medicine.
Sergiusz Wesołowski +14 more
doaj +1 more source
Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity
Frontiers in Cardiovascular Medicine, 2021 The understanding of the electrophysiological mechanisms that underlie mechanosensitivity of the sinoatrial node (SAN), the primary pacemaker of the heart, has been evolving over the past century.
Daniel Turner +6 more
doaj +1 more source
Estudio del sistema de marcapasos auriculares en el corazón del perro [PDF]
, 1998 Inclou referències ...
Bethencourt, Armando +4 more
core
La découverte de l’ivabradine (Procoralan®), inhibiteur sélectif du courant pacemaker If : Une nouvelle approche thérapeutique des cardiopathies ischémiques [PDF]
, 2006 L’inhibition du courant pacemakerIf est une cible idéale pour réduire de façon sélective la fréquence cardiaque et constitue une approche thérapeutique attractive pour les cardiopathies ischémiques.
Vilaine, Jean-Paul
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand +2 more
wiley +1 more source
Temporary neonatal atrial pacing through the umbilical venous route: A novel technique
Annals of Pediatric Cardiology, 2011 Atrial pacing in the neonate is rarely done due to constraints of equipment, technical knowhow, and risk of complications. We describe a novel method of atrial pacing in the new born using equipment readily available in any intensive care unit.
Hiren N Doshi, Seema T Lokare
doaj +1 more source
TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling [PDF]
, 2019 Calcium is an important second messenger required not only for the excitation-contraction coupling of the heart but also critical for the activation of cell signaling pathways involved in the adverse cardiac remodeling and consequently for the heart ...
Calderón Sánchez, Eva María +7 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu +2 more
wiley +1 more source
The G-protein–gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation [PDF]
, 2013 Parasympathetic regulation of sinoatrial node (SAN) pacemaker activity modulates multiple ion channels to temper heart rate. The functional role of the G-protein–activated K+ current (IKACh) in the control of SAN pacemaking and heart rate is not ...
Audoubert, Matthieu +14 more
core +3 more sources