Quantitative detection of siRNA and single-stranded oligonucleotides: relationship between uptake and biological activity of siRNA [PDF]
Marita Overhoff
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Genetic Engineering Methods in Primary T Cells
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
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ATG16L1 promotes cell migration and invasion in high glucose-induced retinal capillary endothelial cells. [PDF]
Gao X, Xie P, Feng W, Han J, Tan X.
europepmc +1 more source
Knockdown of C‐terminal Src kinase by siRNA‐mediated RNA interference augments T cell receptor signaling in mature T cells [PDF]
Torkel Vang+7 more
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Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu+14 more
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Photothermal Therapeutic Gold Nanoparticles Loaded with PD-L1 siRNA Enhanced Killing of NSCLC Cells by Immune Cells. [PDF]
Gao L+11 more
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Transfection of human tumour cells with Mre11 siRNA and the increase in radiation sensitivity and the reduction in heat-induced radiosensitization [PDF]
Mengchang Xu+6 more
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Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
wiley +1 more source