A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing. [PDF]
Meng Q +6 more
europepmc +1 more source
Role of EMP2 and Del-1 in Tamoxifen-resistant Breast Cancer Cells. [PDF]
Lee IH +9 more
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Efficacy of Bioengineered PD-L1 siRNA for Immunotherapy Against Non-Small Cell Lung Cancer Cells. [PDF]
Batra N, Tu MJ, Guan S, Riess JW, Yu AM.
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Targeted inhibition of the BDNF/AKT/mTOR pathway in the inferior colliculus ameliorates salicylate-induced tinnitus in rats. [PDF]
Lin J, Wu J, Wang Y, Huo Y, Zhang J.
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Roles of Ceramide Glucosyltransferase in Controlling Cerebral Microvascular Endothelial Integrity and Angiogenesis Post-Ischemia/Reperfusion. [PDF]
Mohamud Yusuf A +9 more
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YBX1 regulates RNA polymerase III transcripts to prevent inflammation. [PDF]
Strilets TI +2 more
europepmc +1 more source
An Ocular Surface-Targeting Nucleic Acid Hydrogel for Efficient Dry Eye Disease Treatment. [PDF]
Liu Y +12 more
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A scalable platform for dumbbell siRNA production using engineered <i>Td</i> PIE in probiotic <i>E. coli</i>. [PDF]
Huang Z +10 more
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[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma. [PDF]
Kang W +10 more
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