Results 201 to 210 of about 317,404 (266)

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

Penetratin Decoration Increases RNAi Silencing Effects of Polymeric Carriers. [PDF]

Chem Mater
Drago SE, Cabibbo M, Scialabba C, Craparo EF, Cavallaro G.   +4 more
europepmc   +1 more source

Long non-coding RNA (lncRNA) <i>CDKN2A-DT</i> promotes proliferation, migration, and invasion of oral squamous cell carcinoma via the PI3K/AKT/mTOR axis. [PDF]

Transl Cancer Res
Liao K, Lv W, Feng B, Su X, Huang X.
europepmc   +1 more source

Molecular Dynamics Simulation-Assisted siRNA Design for Dual-Ubiquitinated SKP2 Silencing via Ago2 Anchoring in Breast Cancer. [PDF]

ACS Omega
Gupta MK, Sudandiradoss C.
europepmc   +1 more source

Proteasome subunit PSMD1 is a key therapeutic target in multiple myeloma.

Blood
Du T, Fang T, Pillai S, Ray A, Wang M, Wan X, Wen K, Liu Y, Xu J, Musa MA, Liu X, Fulciniti M, Munshi NC, Garbicz F, Carrasco RD, Yao Y, Zhang Z, Song Y, Anderson KC.   +18 more
europepmc   +1 more source

Engineered microtissue systems for identifying the roles of Wnt and YAP signaling in hepatoblast differentiation and organization. [PDF]

Mater Today Bio
Grenci B, Tsai A, Zobus K, Underhill GH.
europepmc   +1 more source

Synthetic short RNA in cancer. [PDF]

Front Oncol
Tomita T, Minagawa K, Hiratsuka S.
europepmc   +1 more source

Correction to "Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism". [PDF]

J Oncol
europepmc   +1 more source

Albumin Pre-Coating Enhances Intracellular siRNA Delivery of Multifunctional Amphiphile/siRNA Nanoparticles [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source