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Detection of siRNAs and miRNAs
2008Small RNAs such as small interfering RNAs (siRNAs) and microRNAs (miRNAs) play crucial roles in establishing general host defense mechanisms against viral infections in plants and the development of disease symptoms. Understanding these fundamental processes requires the sensitive and specific detection of small RNA species.
Kauppinen, S., Havelda, Z.
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Targeting Oncogenes with siRNAs
2008Current cancer chemotherapies heavily rely on the unspecific inhibition of proliferating cells. This lack of tumour cell specificity results in severe toxic side effects and may only hardly affect quiescent cancer stem cells consequently leading to relapse. Since oncogenes are exclusively expressed in malignant and pre-malignant cells, they may provide
openaire +2 more sources
Annealing siRNAs to Produce siRNA Duplexes
Cold Spring Harbor Protocols, 2006openaire +2 more sources
Recent advances in siRNA delivery mediated by lipid-based nanoparticles
Advanced Drug Delivery Reviews, 2020Hiroyuki Koide, Sei Yonezawa
exaly
Strategies, design, and chemistry in siRNA delivery systems
Advanced Drug Delivery Reviews, 2019Daniel Griffith Anderson +2 more
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