Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation. [PDF]
PLoS ONE, 2012 OBJECTIVE: Osteogenic repair in response to bone injury is characterized by activation and differentiation of mesenchymal stem cells (MSCs) to osteoblasts. This study determined whether activation of Sirt-1 (a NAD(+)-dependent histone deacetylase) by the
Mehdi Shakibaei +6 more
doaj +12 more sources
Research trends of selective internal radiation therapy for liver cancer: a bibliometric analysis [PDF]
Radiation OncologyBackground Liver cancer is a major contributor to cancer-related mortality. Selective internal radiation therapy (SIRT) for liver cancer has garnered increasing attention.
Mingkun Liu +3 more
doaj +2 more sources
Sequential surgery following Yttrium-90 resin microspheres combined with targeted therapy and immunotherapy for primary hepatocellular carcinoma: a case report [PDF]
Discover OncologyPrimary hepatocellular carcinoma (HCC) is a prevalent malignancy in China, often diagnosed at intermediate to advanced stages, limiting the feasibility of curative surgical resection. Yttrium-90 selective internal radiation therapy (90Y-SIRT) has emerged
Fang-Yuan Hu +5 more
doaj +2 more sources
Radiation safety aspects of 90Y bremsstrahlung radiation produced from radiation shielding apparatus using the Monte Carlo simulation [PDF]
Nuclear Technology and Radiation Protection, 2021 Selective internal radiation therapy using an 90Y labelled microsphere is increasingly used to treat hepatocellular carcinoma. Based on its properties, 90Y can produce bremsstrahlung radiation which is essential for post-treatment localisation ...
Jumpee Chayanit +4 more
doaj +1 more source
CardioVascular and Interventional Radiology, 2022 AbstractSelective internal radiation therapy represents an endovascular treatment option for patients with primary liver malignancies, in different clinical stages. Potential applications of this treatment are in early-stage hepatocellular carcinoma, as a curative option, or in combination with systemic treatments in intermediate and advanced-stages ...
Francesca Romana Ponziani +10 more
openaire +2 more sources
Yttrium-90 transarterial radioembolization for liver metastases from medullary thyroid cancer
European Thyroid Journal, 2023 Objectives: Liver metastases occur in 45% of patients with advanced metastatic medullary thyroid cancer (MTC). Transarterial radioembolization (TARE) has been proposed to treat liver metastases (LM), especially in neuroendocrine tumors.
Luciana Puleo +15 more
doaj +1 more source
Advances in Radiation Oncology, 2021 Purpose: Selective internal radiation therapy (SIRT) is administered to treat tumors of the liver and is generally well tolerated. Although widely adopted for its therapeutic benefits, SIRT is rarely combined with external beam radiation therapy (EBRT ...
Elliot Abbott, DPhil, MSc +6 more
doaj +1 more source
SIRT-1 is required for release of enveloped enteroviruses
eLife, 2023 Enterovirus D68 (EV-D68) is a re-emerging enterovirus that causes acute respiratory illness in infants and has recently been linked to Acute Flaccid Myelitis.
Alagie Jassey +7 more
doaj +1 more source
Comparative Study of SIRT1 Expression in Hepatitis B Virus, Hepatitis C Virus, and Hepatocellular Carcinoma Patients [PDF]
Egyptian Journal of Medical Research, 2022 Background and Aim: The most common form of primary liver cancer in adults is hepatocellular carcinoma (HCC), and it is the most common cause of death in people with cirrhosis.
Ahmed Ibrahim +3 more
doaj +1 more source
Value of hysteroscopy in management of unexplained infertility
Asian Pacific Journal of Reproduction, 2014 Objective: To assess the value of hysteroscopy in unexplained infertility. Methods: 200 infertile women in whom standard infertility investigations revealed no abnormalities were included in the study between January 2009 and December 2013.
Aisha M. Elbareg +3 more
doaj +1 more source