Results 21 to 30 of about 35,822 (223)

Potential Antiaging Effects of DLBS1649, a Centella asiatica Bioactive Extract

Journal of Experimental Pharmacology, 2021
Agung H Karsono,1 Olivia M Tandrasasmita,1 Guntur Berlian,1 Raymond R Tjandrawinata2,3 1Section of Molecular Pharmacology, Research Innovation and Invention, Dexa Laboratories of Biomolecular Sciences, Dexa Medica, Cikarang, West Java 17550, Indonesia ...
Karsono AH, Tandrasasmita OM, Berlian G, Tjandrawinata RR   +3 more
doaj  

Sirtuins 1–7 expression in human adipose-derived stem cells from subcutaneous and visceral fat depots: influence of obesity and hypoxia [PDF]

, 2016
The sirtuin family comprises seven NAD+-dependent deacetylases which control the overall health of organisms through the regulation of pleiotropic metabolic pathways.
Di Rocco, Giuliana, Mariani, Stefania, Petrangeli, Elisa, Russo, Matteo A., Salvatori, Luisa, Toietta, Gabriele   +5 more
core   +1 more source

Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease

Lipids in Health and Disease, 2021
Background Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with mitochondrial damages. However, the exact mechanisms involved in the etiology of the disease are not clear.
Yan Jiang, Duankai Chen, Qiming Gong, Qunqing Xu, Dong Pan, Feiyan Lu, Qianli Tang   +6 more
doaj   +1 more source

Sparse-View Neutron CT Reconstruction Using a Modified Weighted Total Difference Minimization Method

Applied Sciences, 2021
Indirect neutron imaging is an effective method for nondestructive testing of spent nuclear fuel elements. Considering the difficulty of obtaining experimental data in a high-radiation environment and the characteristic of high noise of neutron images ...
Yapeng Wu, Min Yang, Linfeng He, Qiang Lin, Meimei Wu, Zhengyao Li, Yuqing Li, Xiaoguang Liu   +7 more
doaj   +1 more source

Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding [PDF]

, 2016
Funding: The Scottish Government's Rural and Environment Science and Analytical Services Division.Peer ...
Drew, Janice E., Farquharson, Andrew J., Horgan, Graham W, Williams, Lynda M.   +3 more
core   +1 more source

Effect of high-dose glucocorticoids on markers of inflammation and bone metabolism in patients with primary glomerular disease

Kidney & Blood Pressure Research, 2022
Background: Glucocorticoids are one of the most commonly used drugs for treatment of inflammatory and autoimmune diseases. Sirtuin-1 (SIRT-1) belongs to family of proteins involved in protection against inflammation and oxidative stress.
Katarzyna Pęczek, Michał Nowicki
doaj   +1 more source

Quantitative pretreatment VOI analysis of liver metastases 99mTc-MAA SPECT/CT and FDG PET/CT in relation with treatment response to SIRT [PDF]

, 2013
Using quantitive VOI analysis, the percentage Tc-99m-MAA uptake and SUVmax and mean values of liver metastases obtained prior to SIRT were related to treatment response using both a lesion-based and clinical dichotomous approach. Based on the VOI % of Tc-
Beels, L, Brugman, E, D'Asseler, Yves, De Spiegeleer, Bart, Maes, A, Mees, Gilles, Stellamans, K, Van De Wiele, Christophe   +7 more
core   +2 more sources

Non-Invasive Imaging Biomarkers to Predict the Hepatopulmonary Shunt Fraction Before Transarterial Radioembolization in Patients with Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2023
Charlie Alexander Hamm,1,2,* Felix Busch,1,3,* Anna Pöhlmann,4 Annabella Shewarega,5 Yubei He,1 Robin Schmidt,1 Han Xu,1 Gero Wieners,1 Bernhard Gebauer,1 Lynn Jeanette Savic1,2 1Department of Radiology, Campus Virchow-Klinikum, Charité ...
Hamm CA, Busch F, Pöhlmann A, Shewarega A, He Y, Schmidt R, Xu H, Wieners G, Gebauer B, Savic LJ   +9 more
doaj  

Sirtuin functions and modulation: from chemistry to the clinic [PDF]

, 2016
Sirtuins are NAD+ -dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, DNA repair, cell ...
Altucci, Lucia, Carafa, Vincenzo, Cuomo, Francesca, Forgione, Mariantonietta, Hailu, GEBREMEDHIN SOLOMON, Jarho, Elina, Lahtela Kakkonen, Maija, Mai, Antonello, Rotili, Dante, Serretiello, Enrica   +9 more
core   +2 more sources

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source