Results 171 to 180 of about 65,348 (268)

Acupuncture attenuates hypertension-induced myocardial hypertrophy: role of the SIRT1/NF-κ B/MAPK signaling axis in the hypothalamic paraventricular nucleus. [PDF]

Front Neurosci
Zhang J, Wu J, Wang P, Wang B, Li S, Luo G, Xiao Z, Liu Q.   +7 more
europepmc   +1 more source

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

The FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

Epigenetic control of cellular plasticity in breast cancer progression

The FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey, Elizabeth Podleszanski, William J. Muller   +2 more
wiley   +1 more source

Pharmacological activation of SIRT1 alleviates sepsis-associated acute kidney injury by improving renal mitochondrial energy metabolism. [PDF]

Ren Fail
Zhu R, Yang H, Liu L, Gao Y, Gao X.
europepmc   +1 more source

SIRT1 and anxiety [PDF]

Nature Genetics, 2012
openaire   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Association Between Serum Amylin, Irisin, and Sirtuin 1 in Male Patients with Type 2 Diabetes and Diabetic Nephropathy. [PDF]

Int J Endocrinol Metab
Sabih Wajdi S, Mohyadini M, Abdlwhab HM, E Jassim W, Bathaie SZ.   +4 more
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

The Role of SIRT1 in Mediating Bone Marrow Edema and Its Interface With Bone Remodeling. [PDF]

Immun Inflamm Dis
Chen Y, Li X, Zheng Z, Liu Z, Xu T, Tang Y.   +5 more
europepmc   +1 more source