Results 211 to 217 of about 10,461 (217)

ERK1/2 regulates SIRT2 deacetylase activity

Biochemical and Biophysical Research Communications, 2013
Hangun Kim, You Hee Choi, Sung Ho Lee
exaly  

Role of microglial SIRT2 on neuroinflammation

Sirtuin 2 (SIRT2) has been associated with aging, age-related pathologies and neuroinflammation. In the present study, we have analyzed in mice the implication of microglial sirtuin 2 in two different models of neuroinflammation: an acute pro-inflammatory stimulus (intraperitoneal injection of LPS) and neurodegeneration (mouse model of Alzheimer ...
openaire   +1 more source

Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin

Experimental Dermatology, 2014
Lei Qiang, Yu-Ying He, Mei Ming
exaly  

A Small‐Molecule SIRT2 Inhibitor That Promotes K‐Ras4a Lysine Fatty‐Acylation

ChemMedChem, 2019
Hui Jing, Ji Cao, Nicole A Spiegelman
exaly  

Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53

Biochemical and Biophysical Research Communications, 2008
Kwang-Hyun Baek, Dae-Won Kim, Chang-Yeol Yeo   +2 more
exaly  

Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia

Frontiers in Immunology, 2019
Tytti Heinonen, Didier Le Roy, Thierry Roger   +2 more
exaly  

Selective inhibition of SIRT2: A disputable therapeutic approach in cancer therapy

Bioorganic Chemistry
Gökçen Eren
exaly