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Role of microglial SIRT2 on neuroinflammation
Sirtuin 2 (SIRT2) has been associated with aging, age-related pathologies and neuroinflammation. In the present study, we have analyzed in mice the implication of microglial sirtuin 2 in two different models of neuroinflammation: an acute pro-inflammatory stimulus (intraperitoneal injection of LPS) and neurodegeneration (mouse model of Alzheimer ...openaire +1 more source
Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53
Biochemical and Biophysical Research Communications, 2008Kwang-Hyun Baek +2 more
exaly
SIRT2 regulates insulin sensitivity in insulin resistant neuronal cells
Biochemical and Biophysical Research Communications, 2016Chinmoy Dey
exaly
Sirt2 suppresses inflammatory responses in collagen-induced arthritis
Biochemical and Biophysical Research Communications, 2013exaly
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
Aging Cell, 2007exaly
Selective inhibition of SIRT2: A disputable therapeutic approach in cancer therapy
Bioorganic ChemistryGökçen Eren
exaly