Results 141 to 150 of about 43,355 (289)
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China [PDF]
, 2021 Yao Yao +4 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever +4 more
wiley +1 more source
Evaluation of potential aging biomarkers in healthy individuals: telomerase, AGEs, GDF11/15, sirtuin 1, NAD+, NLRP3, DNA/RNA damage, and klotho [PDF]
, 2023 Pavel Borský +10 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We recruited non‐pregnant women (NP), women in early pregnancy (EP) and late pregnancy (LP) for isolation of endothelial colony forming cells (ECFCs) via density gradient centrifugation. Plasma supernatant was collected for analysis of markers of glucose and lipid metabolism (fasting glucose, triglycerides, cholesterol, low ...
Marie‐Therese Weiser‐Fuchs +14 more
wiley +1 more source
14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
The Journal of Physiology, EarlyView.Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
Sirtuin 1 Mediates Hydrogen Sulfide-induced Cytoprotection Effects in Neonatal Mouse Cardiomyocytes.
, 2017 Aijun Liu +5 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson +6 more
wiley +1 more source