Results 151 to 160 of about 29,404,575 (242)

Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis

Oral Diseases, EarlyView.
ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner, Fatma Soysal, Ceren Gokmenoglu, Muhittin A. Serdar, Zeliha Guney   +4 more
wiley   +1 more source

Sleep-wake and circadian behavior in brain-specific sirtuin 1 knockout mice and effects of nicotinamide mononucleotide supplementation. [PDF]

Sci Rep
Sakai N, Yoshimoto R, Yamaguchi D, Nishino S.   +3 more
europepmc   +1 more source

FGF21/sirtuin 1 axis mediates the cardioprotective effects of high-intensity interval training against doxorubicin-induced cardiotoxicity by reducing inflammatory and oxidative stress. [PDF]

Exp Physiol
Farahani M, Gaeini AA, Ghardashi Afousi A, Borjian Fard M.   +3 more
europepmc   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Sirtuin 1 as an emerging exerkine in the aging process: unveiling its multifaceted biological roles. [PDF]

Biogerontology
de Araújo Leite PL, Maciel LA, Patricio RCB, Pereira GLC, de Oliveira Lamounier AS, da Silva Aguiar S, Sousa CV, de Sousa Neto IV, Simões HG.   +8 more
europepmc   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Differential Expression of Visfatin, Sirtuin-1, and Interleukin-18 in Ankylosing Spondylitis Patients: A Comparative Study of Etanercept-Treated versus Newly Diagnosed Patients. [PDF]

Iran J Med Sci
Asgarian A, Hesari Z, Aghaei M, Faghhian Z, Malakouti R, Besharat S, Sineh Sepehr K.   +6 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Comment on “Renal Protective Effect of Sirtuin 1”

Journal of Diabetes Research, 2015
Kultigin Turkmen
doaj   +1 more source

Deciphering the Role of Sirtuin-1 Gene Polymorphism in Diabetic Nephropathy: A Systematic Review and Meta-Analysis. [PDF]

J Diabetes Res
Moin H, Asad M, Waseem M, Zafar S, Syed H, Syed R, Hussain M.   +6 more
europepmc   +1 more source