Results 161 to 170 of about 63,033 (309)

Adverse Outcomes and Associated Factors Among Children and Youths With Diabetes Mellitus in East Africa: A Systematic Review and Meta‐Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To identify adverse outcomes and factors associated with diabetes mellitus among children and youths in East Africa. Design This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines.
Chalie Marew Tiruneh, Marilyn Cruickshank, Muhammad Chutiyami, Lin Perry   +3 more
wiley   +1 more source

The effects of resveratrol on cyclooxygenase-1 and -2, nuclear factor kappa beta, matrix metalloproteinase-9, and sirtuin 1 mRNA expression in hearts of streptozotocin-induced diabetic rats

, 2011
Atiye Seda Yar, Sevda Menevşe, Ebru Alp
openalex   +1 more source

Sirtuin 1 (SIRT1); AMP-activated protein kinase (AMPK) [PDF]

, 2014
Jong‐Wan Park
openalex   +1 more source

Dysregulation of lncRNA OIP5‐AS1 participants in the progression of diabetic retinopathy and affects the proliferation in retinal vascular endothelial cell

Journal of Diabetes Investigation, EarlyView.
OIP5‐AS1 was down‐regulated in T2DM‐DR patients and regulated cellular functions via targeting miR‐181a‐5p. ABSTRACT Aims This study was to ascertain the clinical performance of OIP5‐AS1 in diabetic retinopathy (DR) and its molecular mechanism in the disease progression. Materials and Methods Subjects included 85 healthy controls, 79 patients with type
Ziwen Yin, Jingyun Dong, Yachao Meng, Zhiqiang Yang, Chunhong Zhao, Qiuyun Wu   +5 more
wiley   +1 more source

MicroRNA-506 regulates apoptosis in retinoblastoma cells by targeting sirtuin 1

Cancer Management and Research, 2019
Zhidu Song,1 Hailiang Wang,2 Fangwei Zong,1 Chao Zhu,1 Ying Tao3 1Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin 130022, People’s Republic of China; 2Department of Neurosurgery, The Second Hospital of Jilin ...
Song Z, Wang H, Zong F, Zhu C, Tao Y
doaj  

Complex Interplay Between Obesity and BRCA1/2‐Associated Breast Cancer: An Overview

Obesity Reviews, EarlyView.
ABSTRACT The steadily increasing prevalence of obesity and its association with a growing number of malignancies, including breast cancer, has made this disease spectrum an urgent and critical public health priority, demanding immediate attention and comprehensive action.
Cinzia Giordano, Marianna Puzzo, Rocco Malivindi, Debora Cristofaro, Luca Gelsomino, Daniela Bonofiglio, Carlo Capalbo, Sebastiano Andò, Ines Barone, Stefania Catalano   +9 more
wiley   +1 more source

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

, 2012
Weijing Cai, Maya Ramdas, Li Zhu, Xue Chen, Gary E. Striker, Helen Vlassara   +5 more
openalex   +1 more source

The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling [PDF]

, 2015
Jun Wei, Archit K. Ghosh, Haiyan Chu, Feng Fang, Monique Hinchcliff, Jiucun Wang, Roberta Gonçalves Marangoni, John Varga   +7 more
openalex   +1 more source

Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette, Chloé Ilbert, Sébastien Aimé, Hoai‐Nam Truong, Marielle Adrian, Stéphane Bourque   +5 more
wiley   +1 more source

Cathepsin Cleavage of Sirtuin 1 in Endothelial Progenitor Cells Mediates Stress-Induced Premature Senescence

, 2012
Jun Chen, Sandhya Xavier, Eliza Moskowitz-Kassai, Robert Chen, Connie Y. Lu, Kyle Sanduski, Aleš Špes, Boris Turk, Michael S. Goligorsky   +8 more
openalex   +1 more source