Results 221 to 230 of about 63,033 (309)

Sirtuin 1 in rat orthotopic liver transplantation: An IGL-1 preservation solution approach

open access: hybrid, 2015
Eirini Pantazi   +8 more
openalex   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

open access: yesAdvanced Functional Materials, Volume 35, Issue 42, October 15, 2025.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao   +8 more
wiley   +1 more source

Sirtuin 1 independent effects of resveratrol in INS-1E β-cells [PDF]

open access: green, 2017
Cihan Süleyman Erdogan   +3 more
openalex   +1 more source

The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function. [PDF]

open access: yesCurr Issues Mol Biol
Patyal P   +8 more
europepmc   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang   +11 more
wiley   +1 more source

Correlation between Sirtuin 1 downregulation and reduced vitamin D receptor expression in patients with diabetic neuropathy. [PDF]

open access: yesActa Diabetol
Latini A   +9 more
europepmc   +1 more source

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang   +20 more
wiley   +1 more source

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