Results 131 to 140 of about 18,693 (245)

Principles of meiotic chromosome assembly revealed in S. cerevisiae [PDF]

, 2019
During meiotic prophase, chromosomes organise into a series of chromatin loops emanating from a proteinaceous axis, but the mechanisms of assembly remain unclear.
A Goloborodko, A Hayashi, A Lengronne, A Storlazzi, A Tedeschi, AL Sanborn, AV Smith, B Bonev, D Thacker, D Zickler, E Alipour, E Crane, E Trelles-Sticken, EF Glynn, EP Nora, EP Nora, F Klein, G Fudenberg, G Fudenberg, G Fudenberg, G Wutz, GA Busslinger, H Jin, H Muller, H Tjong, H Wong, J Dekker, J Dekker, J Gassler, J Li, JA Carballo, JF Marko, JHI Haarhuis, JM Belton, JR Dixon, K Challa, K Nasmyth, KG Alavattam, L Lazar-Stefanita, L Patel, L Xu, M Ito, M Merkenschlager, M Sym, M Sym, MN Conrad, N Naumova, N Servant, NJ Petela, NM Hollingsworth, O Crawley, P Eastman, P Eastman, P Kerpedjiev, PB Møens, Q Jin, S Heinz, S Maleki, S Panizza, SA Schalbetter, SSP Rao, SSP Rao, T Mizuguchi, T Sakuno, TS Hsieh, VV Subramanian, W Schwarzer, Y Blat, Y Kakui, Y Wang   +69 more
core   +2 more sources

PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion. [PDF]

Nat Struct Mol Biol, 2023
Psakhye I, Kawasumi R, Abe T, Hirota K, Branzei D.   +4 more
europepmc   +1 more source

The Drosophila mei-S332 gene promotes sister-chromatid cohesion in meiosis following kinetochore differentiation. [PDF]

, 1992
Anne W. Kerrebrock, W Y Miyazaki, D Birnby, Terry L. Orr‐Weaver   +3 more
openalex   +1 more source

The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent manner [PDF]

, 2007
Proper sister chromatid cohesion is critical for maintaining genetic stability. San is a putative acetyltransferase that is important for sister chromatid cohesion in Drosophila melanogaster, but not in budding yeast.
Chu, Chih-Wen, Hou, Fajian, Kong, Xiangduo, Yokomori, Kyoko, Zou, Hui   +4 more
core   +2 more sources

Topology and structure of an engineered human cohesin complex bound to Pds5B

Nature Communications, 2016
Cohesin is a ring-shaped protein complex that structures chromatin and mediates sister chromatid cohesion. Here the authors rigidify cohesin using engineered Smc1 and Smc3 and generated 3D models showing how Pds5B forms an integral part of the cohesin ...
Michael T. Hons, Pim J. Huis in ‘t Veld, Jan Kaesler, Pascaline Rombaut, Alexander Schleiffer, Franz Herzog, Holger Stark, Jan-Michael Peters   +7 more
doaj   +1 more source

Alternative Functional rad21 Paralogs in Fusarium oxysporum

Frontiers in Microbiology, 2019
Cohesin, the sister chromatid cohesion complex, is an essential complex that ensures faithful sister chromatid segregation in eukaryotes. It also participates in DNA repair, transcription and maintenance of chromosome structure.
Manish Pareek, Yael Almog, Vinay Kumar Bari, Einat Hazkani-Covo, Itay Onn, Shay Covo   +5 more
doaj   +1 more source

Sister chromatid cohesion is mediated by individual cohesin complexes [PDF]

Eukaryotic genomes are organized by loop extrusion and sister chromatid cohesion, both mediated by the multimeric cohesin protein complex. Understanding how cohesin holds sister DNAs together, and how loss of cohesion causes age-related infertility in ...
Brown, Jill, Buckle, Veronica, Gerlich, Daniel Wolfram, Green, Charlotte, Kolesnikova, Sofia, Nasmyth, Kim Ashley, Ochs, Fena, Pytowski, Lior, Schermelleh, Lothar, Szczurek, Aleksander   +9 more
core   +2 more sources

Requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

The EMBO Journal
Sister chromatid cohesion is mediated by the cohesin complex. In mitotic prophase cohesin is removed from chromosome arms in a Wapl- and phosphorylation-dependent manner. Sgo1-PP2A protects pericentromeric cohesion by dephosphorylation of cohesin and its
Susanne Hellmuth, Olaf Stemmann
doaj   +1 more source

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin. [PDF]

Nucleic Acids Res, 2023
van Schie JJM, de Lint K, Molenaar TM, Moronta Gines M, Balk JA, Rooimans MA, Roohollahi K, Pai GM, Borghuis L, Ramadhin AR, Corazza F, Dorsman JC, Wendt KS, Wolthuis RMF, de Lange J.   +14 more
europepmc   +1 more source

Precocious activation of APC/C-Cdh1 at pre-anaphase causes genome instability [PDF]

, 2008
Faithful chromosome segregation and thereby accurate gene transmission are crucial for all organisms. Until proper attachment of the mitotic spindle to the kinetochore is established, the ubiquitin ligase (E3) Cdc20-activated APC/C (anaphase promoting ...
Asuka Suzuki, Ayumu Yamamoto, Kazuhiro Toda, Masahiro Uritani, Masaru Ueno, Takanori Ohyoshi, Takashi Ushimaru   +6 more
core   +1 more source