Results 121 to 130 of about 11,947 (194)

Topology and structure of an engineered human cohesin complex bound to Pds5B

Nature Communications, 2016
Cohesin is a ring-shaped protein complex that structures chromatin and mediates sister chromatid cohesion. Here the authors rigidify cohesin using engineered Smc1 and Smc3 and generated 3D models showing how Pds5B forms an integral part of the cohesin ...
Michael T. Hons, Pim J. Huis in ‘t Veld, Jan Kaesler, Pascaline Rombaut, Alexander Schleiffer, Franz Herzog, Holger Stark, Jan-Michael Peters   +7 more
doaj   +1 more source

Alternative Functional rad21 Paralogs in Fusarium oxysporum

Frontiers in Microbiology, 2019
Cohesin, the sister chromatid cohesion complex, is an essential complex that ensures faithful sister chromatid segregation in eukaryotes. It also participates in DNA repair, transcription and maintenance of chromosome structure.
Manish Pareek, Yael Almog, Vinay Kumar Bari, Einat Hazkani-Covo, Itay Onn, Shay Covo   +5 more
doaj   +1 more source

PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion. [PDF]

Nat Struct Mol Biol, 2023
Psakhye I, Kawasumi R, Abe T, Hirota K, Branzei D.   +4 more
europepmc   +1 more source

Is chromatin remodeling required to build sister-chromatid cohesion? [PDF]

Chromosome segregation during mitosis and meiosis depends on the linkage of sister DNA molecules after replication. These links, known as sister-chromatid cohesion, are provided by a multi-subunit complex called cohesin.
Gruber S; Riedel CG; Gregan J; Nasmyth K
core  

Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination [PDF]

, 2004
Sister chromatid cohesion ensures the faithful segregation of chromosomes in mitosis and in both meiotic divisions1, 2, 3, 4. Meiosis-specific components of the cohesin complex, including the recently described SMC1 isoform SMC15, were suggested to be ...
Jessberger, R., Scherthan, H., Christa Heyting, Ekaterina Revenkova, Revenkova, E., Liebe, B., Patricia A. Hunt, Rolf Jessberger, Hunt, P.A., Craig A. Hodges, Eijpe, M., Hodges, C.A., Maureen Eijpe, Heyting, C., Hodges, C., Harry Scherthan, Hunt, P., Bodo Liebe   +17 more
core   +1 more source

Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II

Nature Communications, 2017
Sister chromatid cohesion during meiosis II (MII), maintained by securin-mediated inhibition of separase, is reduced in aged mouse oocytes. Here the authors show that, in MII oocytes, securin levels are reduced by increased destruction by the anaphase ...
Ibtissem Nabti, Rosanna Grimes, Hema Sarna, Petros Marangos, John Carroll   +4 more
doaj   +1 more source

Global view and genetic dissection of genes in sister chromatid cohesion [PDF]

, 2007
The replication and transmission of genetic information from generation to generation is central to every organism. Accomplishment of this daunting task relies on the integrated action of a number of cellular processes in DNA dynamics: DNA replication ...
Xu, Hong
core   +1 more source

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin. [PDF]

Nucleic Acids Res, 2023
van Schie JJM, de Lint K, Molenaar TM, Moronta Gines M, Balk JA, Rooimans MA, Roohollahi K, Pai GM, Borghuis L, Ramadhin AR, Corazza F, Dorsman JC, Wendt KS, Wolthuis RMF, de Lange J.   +14 more
europepmc   +1 more source

MMS22L-TONSL functions in sister chromatid cohesion in a pathway parallel to DSCC1-RFC. [PDF]

Life Sci Alliance, 2023
van Schie JJ, de Lint K, Pai GM, Rooimans MA, Wolthuis RM, de Lange J.   +5 more
europepmc   +1 more source

Integrating Sister Chromatid Cohesion Establishment to DNA Replication. [PDF]

Genes (Basel), 2022
Zuilkoski CM, Skibbens RV.
europepmc   +1 more source