Sister chromatid cohesion and genome stability in vertebrate cells [PDF]
For successful eukaryotic mitosis, sister chromatid pairs remain linked after replication until their kinetochores have been attached to opposite spindle poles by microtubules.
Morrison, C. +4 more
core
Application of neural network-based image analysis to detect sister chromatid cohesion defects. [PDF]
Ikemoto D +5 more
europepmc +1 more source
Precocious activation of APC/C-Cdh1 at pre-anaphase causes genome instability [PDF]
Faithful chromosome segregation and thereby accurate gene transmission are crucial for all organisms. Until proper attachment of the mitotic spindle to the kinetochore is established, the ubiquitin ligase (E3) Cdc20-activated APC/C (anaphase promoting ...
Takanori Ohyoshi +6 more
core +1 more source
Reduced sister chromatid cohesion acts as a tumor penetrance modifier. [PDF]
Wang J +9 more
europepmc +1 more source
Functional Coupling between DNA Replication and Sister Chromatid Cohesion Establishment. [PDF]
Boavida A +3 more
europepmc +1 more source
Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia. [PDF]
Moura-Castro LH +7 more
europepmc +1 more source
Mediators of pre-mRNA splicing regulate sister chromatid cohesion in mammalian cells [PDF]
The ‘endless forms most beautiful’ that populate our planet rely on the process of cell division to ensure equal segregation of the cellular content including the DNA to the two daughter cells. The accurate segregation of chromosomes in eukaryotes relies
Sundaramoorthy, S
core
[Sister chromatid cohesion complex in Eukaryota].
Faithful chromosome segregation in mitosis and meiosis requires the presence of the sister chromatid cohesion complex. The complex, which was initially identified and characterized in yeast Saccharomyces cerevisiae, and subsequently detected in other Eukaryota, is composed of four evolutionarily conserved core subunits (cohesins) Smc1, Smc3, Scc1/Mcd1 ...
Agata, Cena, Anna, Kurlandzka
openaire +1 more source
Regulation of sister chromatid cohesion by nuclear PD-L1. [PDF]
Yu J +10 more
europepmc +1 more source

