Results 171 to 180 of about 921,868 (189)

Heterochromatin and the cohesion of sister chromatids

Chromosome Research, 2009
Heterochromatin, once thought to be the useless junk of chromosomes, is now known to play significant roles in biology. Underlying much of this newfound fame are links between the repressive chromatin structure and cohesin, the protein complex that mediates sister chromatid cohesion.
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Calpain 2 is required for sister chromatid cohesion

Chromosoma, 2010
Calpains form a family of Ca(2+)-dependent cysteine proteases involved in diverse cellular processes. However, the specific functions of each calpain isoform remain unknown. Recent reports have shown that calpain 2 (Capn2) is essential for cell viability. We have recently shown that Capn2 is a nuclear protease associated with chromosomes during mitosis
Magnaghi-Jaulin, Laura, Marcilhac, Anne, Rossel, Mireille, Jaulin, Christian, Benyamin, Yves, Raynaud, Fabrice   +5 more
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A Molecular Determinant for the Establishment of Sister Chromatid Cohesion

Science, 2008
Chromosome segregation, transcriptional regulation, and repair of DNA double-strand breaks require the cohesin protein complex. Cohesin holds the replicated chromosomes (sister chromatids) together to mediate sister chromatid cohesion. The mechanism of how cohesion is established is unknown.
Elçin, Unal, Jill M, Heidinger-Pauli, Woong, Kim, Vincent, Guacci, Itay, Onn, Steven P, Gygi, Douglas E, Koshland   +6 more
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Sister chromatid cohesion along arms and at centromeres

Trends in Genetics, 2005
There is an obvious difference between the regulation of sister chromatid cohesion at centromeres and along chromosome arms during meiosis, because centromeric cohesion, but not arm cohesion, persists throughout anaphase of the first meiotic division. This regional difference of sister chromatid cohesion is also observed during mitosis; the cohesion is
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Sister chromatid cohesion: the beginning of a long and beautiful relationship

Current Opinion in Cell Biology, 2000
Our understanding of the mechanism of sister chromatid cohesion has advanced significantly with the recent identification and characterization of important regulatory factors, structural factors and chromosomal cohesion sites. These analyses reveal a surprisingly complex mechanism of cohesion that is just beginning to be elucidated and exciting ...
D E, Koshland, V, Guacci
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Proteins controlling sister-chromatid cohesion

1997
Prior to the metaphase/anaphase transition of cell division the replicated copies of each chromosome, the sister chromatids, are attached to each other. We use the term ‘sister-chromatid cohesion’ to describe this physical association between the sister chromatids.
T. L. Orr-Weaver, D. P. Moore, A. W. Kerrebrock, S. E. Bickel, D. W. Wyman   +4 more
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Buck the establishment: reinventing sister chromatid cohesion

Trends in Cell Biology, 2010
The time between chromosome replication and segregation can be from hours to decades. Cohesion is thus crucial for identifying replication products as sister chromatids from S-phase until mitosis. Early models posited active sister chromatid tethering reactions in which cohesins deposited onto each sister chromatid are converted to a paired state by ...
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Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism

EMBO Journal, 2001
Hiroto Okayama
exaly  

Regulation of sister chromatid cohesion during the mitotic cell cycle

Science China Life Sciences, 2015
Hongtao Yu, Ge Zheng
exaly  

WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion

Developmental Cell, 2020
Rob Wolthuis, Bente Benedict, Job de Lange   +2 more
exaly