Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq [PDF]
eLife, 2017 Homologous recombination involving sister chromatids is the most accurate, and thus most frequently used, form of recombination-mediated DNA repair. Despite its importance, sister chromatid recombination is not easily studied because it does not result ...
Clémence Claussin +7 more
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Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes [PDF]
Journal of Occupational Medicine and Toxicology, 2009 Background Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. Methods The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune ...
Pongsavee Malinee
doaj +4 more sources
Sister Chromatid Exchange and Genomic Instability in Soft Tissue Sarcomas: Potential Implications for Response to DNA-Damaging Treatments. [PDF]
Sarcoma, 2018 Sarcomas are rare heterogenous malignancies of mesenchymal origin characterised by complex karyotypes but no specific abnormalities. Recurrence is common and metastatic disease carries poor survival despite standard DNA-damaging radiotherapy or ...
Salawu A +5 more
europepmc +5 more sources
Cell Cycle Kinetics and Sister Chromatid Exchange in Mosaic Turner Syndrome [PDF]
LifeTurner syndrome (TS) is caused by a complete or partial absence of an X or Y chromosome, including chromosomal mosaicism, affecting 1 in 2500 female live births.
Miriam Beatriz Goulart +10 more
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Automatic detection of sister chromatid exchanges using machine learning models and image analysis algorithms [PDF]
Scientific ReportsAfter DNA replication, two chromatids with identical genetic information are formed in organisms; these are called sister chromatids. Sister chromatid exchange (SCE) is a recombination event between genetically equivalent sequences.
Mizuo Teraoka +5 more
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Elevated rates of sister chromatid exchange at chromosome ends. [PDF]
PLoS Genetics, 2007 Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome ...
M Katharine Rudd +5 more
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DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. [PDF]
PLoS ONE, 2011 Hyperphosphorylation of RPA2 at serine 4 and serine 8 (S4, S8) has been used as a marker for activation of the DNA damage response. What types of DNA lesions cause RPA2 hyperphosphorylation, which kinase(s) are responsible for them, and what is the ...
Hungjiun Liaw +2 more
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Association between sister chromatid exchange and double minute chromosomes in human tumor cells. [PDF]
Mol Cytogenet, 2015 Xu J +6 more
europepmc +3 more sources
Both RAD5-dependent and independent pathways are involved in DNA damage-associated sister chromatid exchange in budding yeast. [PDF]
AIMS Genet, 2017 Fasullo MT, Sun M.
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Telomere sister chromatid exchange and the process of aging. [PDF]
Aging (Albany NY), 2010 Blagoev KB, Goodwin EH, Bailey SM.
europepmc +3 more sources