Results 11 to 20 of about 26,472 (265)
Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica. [PDF]
New PhytolSummary Polyploidization, followed by genome downsizing, is a recurrent evolutionary cycle that dramatically reshapes genome structure. Newly formed polyploids must quickly adjust their cell division machinery to maintain stable chromosome inheritance, while long‐term stabilization involves rediploidization, returning the genome to a diploid‐like state.
Burns R +6 more
europepmc +2 more sources
Distribution and sources of variability of sister-chromatid exchange frequencies in cattle* [PDF]
Genetics Selection Evolution, 1994 Arruga MV, Moreno C, Catalán J
doaj +2 more sources
Rescue of collapsed replication forks is dependent on NSMCE2 to prevent mitotic DNA damage. [PDF]
PLoS Genetics, 2019 NSMCE2 is an E3 SUMO ligase and a subunit of the SMC5/6 complex that associates with the replication fork and protects against genomic instability. Here, we study the fate of collapsed replication forks generated by prolonged hydroxyurea treatment in ...
Kelvin W Pond +3 more
doaj +1 more source
Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
Nature Communications, 2021 Human SWS1, SWSAP1, and SPIDR interact with RAD51, a critical protein for homology-directed repair. Here the authors reveal roles for the mouse SWS1–SWSAP1–SPIDR complex in inter-homolog recombination, including during meiosis, and sister chromatid ...
Rohit Prakash +16 more
doaj +1 more source
Assessment of the genotoxic potential of temephos [PDF]
Pesticidi i Fitomedicina, 2020 Genotoxic effects of pesticides are of great concern for public health due to the fact that they are widely used for both domestic and industrial purposes.
Cobanoglu Hayal, Cayir Akin
doaj +1 more source
Genotoxic effects of copper sulfate in rabbits [PDF]
Archives of Biological Sciences, 2013 This study was carried out to determine the genotoxic effects of oral application of CuSO4 in rabbits by the chromosome aberration (CA) and sister chromatid exchange (SCE) tests.
Georgieva S., Popov B., Petrov V.
doaj +1 more source
Stem Cell Research, 2020 Bloom syndrome is characterized by severe pre- and postnatal growth deficiency, immune abnormalities, sensitivity to sunlight, insulin resistance, and a high risk for many cancers that occur at an early age. The diagnosis is established on characteristic
Vincent Gatinois +7 more
doaj +1 more source
The Iraqi Journal of Veterinary Medicine, 2015 The present study aims at using the biological techniques in a genotoxicity assessment of low doses of radiation in samples of workers in Al-Tuwaitha site due to decommissioning to radioactive contamination as a result of work.
Abdulsahib K. Ali
doaj +1 more source
Analysis of De Novo HOXA 13 Polyalanine Expansions Supports Replication Slippage Without Repair in Their Generation [PDF]
, 2013 Polyalanine repeat expansion diseases are hypothesized to result from unequal chromosomal recombination, yet mechanistic studies are lacking. We identified two de novo cases of hand‐foot‐genital syndrome (HFGS) associated with polyalanine expansions in ...
Innis, Jeffrey W. +8 more
core +1 more source
"Sister Chromatid Exchanges and Micronuclei in Lymphocyte of Nurses Handling Antineoplastic Drugs" [PDF]
Iranian Journal of Public Health, 2001 Individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. The effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different ...
M Ansari-Lari +3 more
doaj +2 more sources