Results 81 to 90 of about 659,276 (230)
Respirology, Volume 30, Issue 8, Page 736-750, August 2025.Ultralow doses of dextromethorphan significantly alleviate pulmonary fibrosis in bleomycin‐treated mice through restoring the redox balance. Add‐on dextromethorphan improves the effects of pirfenidone in both bleomycin‐treated mice and patients with pulmonary fibrosis.
Jie Huang +12 more
wiley +1 more source
A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase [PDF]
, 2015 A new colorimetric method has been developed to screen transaminases using an inexpensive amine donor. The assay is sensitive, has a low level of background coloration, and can be used to identify and profile transaminase activities against aldehyde and ...
Baud, D +4 more
core +1 more source
Physiological Reports, Volume 13, Issue 15, August 2025.Abstract The association between metabolic dysfunction–associated steatotic liver disease (MASLD) and cardiovascular disease is well characterized; however, the underlying mechanism is incompletely understood. Interestingly, hepatocyte‐specific silencing of dipeptidyl peptidase 4 (DPP4) prevents liver fibrosis and adipose tissue inflammation; however ...
Natasha A. Trzaskalski +8 more
wiley +1 more source
Journal of the Pakistan Medical AssociationObjective: To explore how metformin, alone or in conjunction with sitagliptin, affects the leptin/adiponectin ratio in obese type 2 diabetes mellitus patients.
Hala Aqeel Shams +2 more
doaj +1 more source
Update: Enzymatische Synthese für industrielle Anwendungen
Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer +4 more
wiley +1 more source
Effects of the sodium–glucose co-transporter 2 inhibitor dapagliflozin in patients with type 2 diabetes and Stages 3b–4 chronic kidney disease [PDF]
, 2017 BACKGROUND: The sodium–glucose co-transporter 2 inhibitor dapagliflozin decreases haemoglobin A1c (HbA1c), body weight, blood pressure (BP) and urinary albumin:creatinine ratio (UACR) in patients with type 2 diabetes.
Cain, V +5 more
core +1 more source
An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer +4 more
wiley +1 more source
Molecular regulation of hormone secretion, growth and apoptosis of GLP-1-producing cells [PDF]
, 2013 Type 2 diabetes (T2D) spreads like an epidemic in today’s society, and there is a great need for new and improved treatments. T2D is characterized by hyperglycemia, resulting from impaired insulin production and insulin resistance in peripheral ...
Kappe, Camilla
core +1 more source
Chemistry &Biodiversity, Volume 22, Issue 7, July 2025.This graphical abstract represents the extraction, characterization, and biological evaluation of bioactive compounds derived from specific plant sources. The top section illustrates Rhus coriaria (sumac) fruit, Punica granatum (pomegranate) peel and Terminalia catappa (Indian almond) leaves', which are known for their rich phytochemical composition ...
Mudassir Nazir +8 more
wiley +1 more source