Results 91 to 100 of about 283,425 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The site frequency spectrum of dispensable genes [PDF]
, 2014 The differences between DNA-sequences within a population are the basis to infer the ancestral relationship of the individuals. Within the classical infinitely many sites model, it is possible to estimate the mutation rate based on the site frequency ...
Franz Baumdicker
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A software toolkit for radio frequency data terminals [PDF]
, 2005 This thesis is concerned with the computer industry of "automatic identification.” Central to automatic identification is the use of barcodes and related technologies, including wireless computer networks and Radio Frequency Data Terminals (RFDTs) RFDTs ...
Buckingham, Andrew
core
The site frequency/dosage spectrum of autopolyploid populations [PDF]
, 2021 The Site Frequency Spectrum (SFS) and the heterozygosity of allelic variants are among the most important summary statistics for population genetic analysis of diploid organisms.
Ribeca, Paolo +2 more
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Site-frequency spectra in CNE-NVRs and non-synonymous sites. [PDF]
, 2014 A) Site-frequency spectra in YRI binned into 3 units. The observed non-synonymous site-frequency spectrum fits a gamma distribution of selective effects (shape = 0.1, rate = 6.25).
Richard Nichols (604329) +2 more
core +1 more source
Floristic, frequency, and vegetation life-form spectra of a cerrado site
Brazilian Journal of BiologyWe used Raunkiaer's system to classify in life-forms the vascular plants present in 12 random 25 m² quadrats of a cerrado site. The study area is covered by cerrado sensu stricto and is located in the Valério fragment, at about 22º13'S and 47º51'W, 760 m
M. A. Batalha, F. R. Martins
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Potential of dynamic spectrum allocation in LTE macro networks [PDF]
Advances in Radio Science, 2015 In recent years Mobile Network Operators (MNOs) worldwide are extensively deploying LTE networks in different spectrum bands and utilising different bandwidth configurations. Initially, the deployment is coverage oriented with macro cells using the lower
H. Hoffmann +5 more
doaj +1 more source