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Genetics and Epigenetics in Asthma [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Asthma is one of the most common respiratory disease that affects both children and adults worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly understood. As technology in genome sequencing progressed, scientific efforts were made to explain and predict asthma’s complexity and heterogeneity, and genome-wide association ...
Eleftherios Zervas   +2 more
exaly   +4 more sources

Mitochondrial Genetics and Epigenetics in Osteoarthritis [PDF]

open access: yesFrontiers in Genetics, 2020
During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated.
Ignacio Rego-Pérez   +3 more
doaj   +4 more sources

Genetics, epigenetics, and pregenetics

open access: yesInternational Journal of Yoga, 2011
Byline: Thaiyar. Srinivasan In the blame game of genetic disorders, genes are credited with the disrupting lives of millions of people around the world. The disruption of any system in the body is blamed as a bad gene effect. Genetics ruling lives of living systems is a Darwinian hangover.
Thaiyar M Srinivasan
doaj   +3 more sources

Genetics and epigenetics of gliomas

open access: yesSwiss Medical Weekly, 2014
Gliomas are the most common primary intrinsic brain tumours. Their classification is based on phenotypic resemblance to normal glial cells (astrocytomas, oligodendrogliomas, mixed oligoastrocytomas) and pathological grading.
Mario Luca Suvà
doaj   +3 more sources

Epigenetics and Genetics of Viral Latency [PDF]

open access: yesCell Host and Microbe, 2016
Viral latency can be considered a metastable, nonproductive infection state that is capable of subsequent reactivation to repeat the infection cycle. Viral latent infections have numerous associated pathologies, including cancer, birth defects, neuropathy, cardiovascular disease, chronic inflammation, and immunological dysfunctions.
Paul Lieberman
exaly   +3 more sources

Inflammatory Bowel Disease: Genetics, Epigenetics and Pathogenesis

open access: yesFrontiers in Immunology, 2015
Inflammatory Bowel Diseases (IBDs) are complex, multifactorial disorders characterized by chronic relapsing intestinal inflammation. Although aetiology remains largely unknown, recent research has suggested that genetic factors, environment, microbiota ...
Italia eLoddo, Claudio eRomano
doaj   +3 more sources

Entanglement of Genetics and Epigenetics in Parkinson’s Disease

open access: yesFrontiers in Neuroscience, 2019
Parkinson disease (PD) is a common neurodegenerative disorder that progresses with age, with an increasing number of symptoms. Some of the efforts to understand PD progression have been focusing on the regulation of epigenetic mechanisms, that generally ...
H. J. van Heesbeen, Marten P. Smidt
doaj   +3 more sources

Epigenetic Regulation in Knee Osteoarthritis

open access: yesFrontiers in Genetics, 2022
Osteoarthritis (OA) is a complicated disease with both hereditary and environmental causes. Despite an increase in reports of possible OA risk loci, it has become clear that genetics is not the sole cause of osteoarthritis.
Zhengyu Cai   +4 more
doaj   +1 more source

Genetics and Epigenetics of Parathyroid Carcinoma

open access: yesFrontiers in Endocrinology, 2022
Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT), characterized by an excessive secretion of parathyroid hormone (PTH) and severe
Francesca Marini   +6 more
doaj   +1 more source

Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves’ Disease

open access: yesFrontiers in Cell and Developmental Biology, 2022
Graves’ disease (GD) is a well-known organ-specific autoimmune disease characterized by hyperthyroidism, goiter, and exophthalmos. The incidence of GD is approximately 2.0–3.0% in China and 0.5–2.0% in Western countries.
Fangyu Zhou   +9 more
doaj   +1 more source

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