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Genetics and Epigenetics in Asthma [PDF]
Asthma is one of the most common respiratory disease that affects both children and adults worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly understood. As technology in genome sequencing progressed, scientific efforts were made to explain and predict asthma’s complexity and heterogeneity, and genome-wide association ...
Eleftherios Zervas +2 more
exaly +4 more sources
Mitochondrial Genetics and Epigenetics in Osteoarthritis [PDF]
During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated.
Ignacio Rego-Pérez +3 more
doaj +4 more sources
Genetics, epigenetics, and pregenetics
Byline: Thaiyar. Srinivasan In the blame game of genetic disorders, genes are credited with the disrupting lives of millions of people around the world. The disruption of any system in the body is blamed as a bad gene effect. Genetics ruling lives of living systems is a Darwinian hangover.
Thaiyar M Srinivasan
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Genetics and epigenetics of gliomas
Gliomas are the most common primary intrinsic brain tumours. Their classification is based on phenotypic resemblance to normal glial cells (astrocytomas, oligodendrogliomas, mixed oligoastrocytomas) and pathological grading.
Mario Luca Suvà
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Epigenetics and Genetics of Viral Latency [PDF]
Viral latency can be considered a metastable, nonproductive infection state that is capable of subsequent reactivation to repeat the infection cycle. Viral latent infections have numerous associated pathologies, including cancer, birth defects, neuropathy, cardiovascular disease, chronic inflammation, and immunological dysfunctions.
Paul Lieberman
exaly +3 more sources
Inflammatory Bowel Disease: Genetics, Epigenetics and Pathogenesis
Inflammatory Bowel Diseases (IBDs) are complex, multifactorial disorders characterized by chronic relapsing intestinal inflammation. Although aetiology remains largely unknown, recent research has suggested that genetic factors, environment, microbiota ...
Italia eLoddo, Claudio eRomano
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Entanglement of Genetics and Epigenetics in Parkinson’s Disease
Parkinson disease (PD) is a common neurodegenerative disorder that progresses with age, with an increasing number of symptoms. Some of the efforts to understand PD progression have been focusing on the regulation of epigenetic mechanisms, that generally ...
H. J. van Heesbeen, Marten P. Smidt
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Epigenetic Regulation in Knee Osteoarthritis
Osteoarthritis (OA) is a complicated disease with both hereditary and environmental causes. Despite an increase in reports of possible OA risk loci, it has become clear that genetics is not the sole cause of osteoarthritis.
Zhengyu Cai +4 more
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Genetics and Epigenetics of Parathyroid Carcinoma
Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT), characterized by an excessive secretion of parathyroid hormone (PTH) and severe
Francesca Marini +6 more
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Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves’ Disease
Graves’ disease (GD) is a well-known organ-specific autoimmune disease characterized by hyperthyroidism, goiter, and exophthalmos. The incidence of GD is approximately 2.0–3.0% in China and 0.5–2.0% in Western countries.
Fangyu Zhou +9 more
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