Results 11 to 20 of about 55,739 (324)

Mitochondrial Genetics and Epigenetics in Osteoarthritis [PDF]

Frontiers in Genetics, 2020
During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated.
Ignacio Rego-Pérez, Alejandro Durán-Sotuela, Paula Ramos-Louro, Francisco J. Blanco   +3 more
doaj   +4 more sources

Food Allergy Genetics and Epigenetics: A Review of Genome-Wide Association Studies. [PDF]

Allergy
In this review, we provide an overview of food allergy genetics and epigenetics aimed at clinicians and researchers. This includes a brief review of the current understanding of genetic and epigenetic mechanisms, inheritance of food allergy, as well as a
Arnau-Soler A, Tremblay BL, Sun Y, Madore AM, Simard M, Kersten ETG, Ghauri A, Marenholz I, Eiwegger T, Simons E, Chan ES, Nadeau K, Sampath V, Mazer BD, Elliott S, Hampson C, Soller L, Sandford A, Begin P, Hui J, Wilken BF, Gerdts J, Bourkas A, Ellis AK, Vasileva D, Clarke A, Eslami A, Ben-Shoshan M, Martino D, Daley D, Koppelman GH, Laprise C, Lee YA, Asai Y.   +33 more
europepmc   +2 more sources

New Insights into the Genetics and Epigenetics of Aging Plasticity. [PDF]

Genes (Basel), 2023
Biological aging is characterized by irreversible cell cycle blockade, a decreased capacity for tissue regeneration, and an increased risk of age-related diseases and mortality.
Zhang J, Zhang J, Wang S, Liu B.
europepmc   +2 more sources

The genetics and epigenetics of satellite centromeres

Genome Research, 2022
Centromeres, the chromosomal loci where spindle fibers attach during cell division to segregate chromosomes, are typically found within satellite arrays in plants and animals.
P. Talbert, S. Henikoff
semanticscholar   +4 more sources

Genetics and epigenetics in obesity. [PDF]

Metabolism, 2019
Obesity is among the most threatening health burdens worldwide and its prevalence has markedly increased over the last decades. Obesity maybe considered a heritable trait.
Kerstin Rohde, M. Keller, Lars la Cour Poulsen, M. Blüher, P. Kovacs, Y. Böttcher   +5 more
semanticscholar   +5 more sources

Genetics, Epigenetics, and Leukemia [PDF]

New England Journal of Medicine, 2010
In this issue of the Journal, Ley and colleagues1 report that somatic mutations in a gene encoding a DNA methyltransferase, DNMT3A, are common in adults with acute myeloid leukemia (AML). They also report that these mutations are associated with discrete molecular and cytogenetic features that have prognostic significance.
Kevin, Shannon, Scott A, Armstrong
openaire   +3 more sources

Genetics and epigenetics of gliomas

Swiss Medical Weekly, 2014
Gliomas are the most common primary intrinsic brain tumours. Their classification is based on phenotypic resemblance to normal glial cells (astrocytomas, oligodendrogliomas, mixed oligoastrocytomas) and pathological grading.
Mario Luca Suvà
doaj   +3 more sources

Genetics and Epigenetics of Manganese Toxicity. [PDF]

Curr Environ Health Rep, 2022
At elevated levels, the essential element manganese (Mn) is neurotoxic and increasing evidence indicates that environmental Mn exposure early in life negatively affects neurodevelopment.
Lindner S, Lucchini R, Broberg K.
europepmc   +2 more sources

The contribution of genetics and epigenetics to MAFLD susceptibility. [PDF]

Hepatol Int
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common liver disease worldwide. The risk of developing MAFLD varies among individuals, due to a combination of environmental inherited and acquired genetic factors.
Moretti V, Romeo S, Valenti L.
europepmc   +2 more sources

Genetics and epigenetics of chronic rhinosinusitis.

Journal of Allergy and Clinical Immunology, 2023
Discerning the genetics and epigenetics of chronic rhinosinusitis (CRS) may optimize outcomes through early diagnostics, personalized and novel therapeutics, and early prognostication.
D. Lal, Tripti Brar, S. Ramkumar, Jingyun Li, A. Kato, Luo Zhang   +5 more
semanticscholar   +3 more sources