Results 31 to 40 of about 50,453 (282)
Tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) in different genomic regions.
Jean S. Fain +4 more
doaj +1 more source
Genetics and epigenetics of liver cancer [PDF]
Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the major factors leading to HCC. This deadly cancer affects more than 500,000 people worldwide and it is quite resistant to conventional chemo- and radiotherapy.
Ozen, C. +7 more
openaire +5 more sources
Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases [PDF]
Bone metabolism consists of a balance between bone formation and bone resorption, which is mediated by osteoblast and osteoclast activity, respectively.
Rotondo, John Charles +19 more
core +1 more source
Epigenetics and genetics of hepatoblastoma: Linkage and treatment
Hepatoblastoma is a malignant embryonal tumor with multiple differentiation modes and is the clearest liver malignancy in children. However, little is known about genetic and epigenetic events in Hepatoblastoma.
Li-ran Zhu +9 more
doaj +1 more source
Interplay between genetics and epigenetics in lung fibrosis [PDF]
Lung fibrosis, including idiopathic pulmonary fibrosis (IPF), is a complex and devastating disease characterised by the progressive scarring of lung tissue leading to compromised respiratory function.
Rajasekar, Poojitha +3 more
core +2 more sources
Epigenetics for the 21st-Century Biology Student
Epigenetics, a rapidly emerging biological science, investigates changes in gene expression without any change to the primary DNA sequence. Epigenetics plays an important role in diverse areas, including nutritional sciences, psychology, and ...
Jonghoon Kang +3 more
doaj +1 more source
Genetics and Epigenetics of Parkinson's Disease
In 1997 a mutation in the a-synuclein (SNCA) gene was associated with familial autosomal dominant Parkinson’s disease (PD). Since then, several loci (PARK1-15) and genes have been linked to familial forms of the disease.
Fabio Coppedè
doaj +1 more source
ALLOSTATIC NEUROPLASTICITY AND EPIGENETIC MECHANISMS IN PERSONALITY DEVELOPMENT [PDF]
Genetics is part of the life of every individual having a great influence not only in terms of the transmission of physical characteristics, but also in terms of the development of the human being.
Oprea-Valentin BUȘU +2 more
doaj
Editorial: Neuronal ceroid lipofuscinosis: molecular genetics and epigenetics [PDF]
Paschalis Nicolaou
doaj +2 more sources
Genetics and epigenetics of melanoma
Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research.
Zhang, Xiao-Ying, Zhang, Pei-Ying
openaire +5 more sources

