Results 51 to 60 of about 50,453 (282)

Effect of Trust in Science on Parental Reactions to Messaging about Children’s Epigenetics-Related Obesity Risk

open access: yesPublic Health Genomics
Introduction: Accumulating evidence suggests that preconception epigenetic changes elevate the risk for obesity throughout the lifespan. Little is known about how parents may react to learning about parent-child epigenetic transmission of ...
Emma M. Schopp   +3 more
doaj   +1 more source

Medical genetics and epigenetics of telomerase

open access: yes, 2011
Telomerase is a specialized reverse transcriptase that extends and maintains the terminal ends of chromosomes, or telomeres. Since its discovery in 1985 by Nobel Laureates Elizabeth Blackburn and Carol Greider, thousands of articles have emerged ...
Herbert, Brittney-Shea   +9 more
core   +1 more source

Genetic and Epigenetic Mechanisms of Psoriasis

open access: yesGenes, 2023
Psoriasis is a disease involving the innate and adaptative components of the immune system, and it is triggered by environmental factors in genetically susceptible individuals. However, its physiopathology is not fully understood yet. Recent technological advances, especially in genome and epigenome-wide studies, have provided a better understanding of
Laura Mateu-Arrom, Lluís Puig
openaire   +3 more sources

Genetics and epigenetics of autism: A Review [PDF]

open access: yesPsychiatry and Clinical Neurosciences, 2017
Autism is a developmental disorder that starts before age 3 years, and children with autism have impairment in both social interaction and communication, and have restricted, repetitive, and stereotyped patterns of behavior, interests, and activities.
Mary M. Y. Waye, Ho Yu Cheng
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Epigenetics—Innovations and Misconceptions

open access: yesNatural Sciences
Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in ...
Bernhard Horsthemke
doaj   +1 more source

Genetics and epigenetics of IBD

open access: yesPharmacological Research, 2020
Inflammatory bowel diseases (IBD) are chronic intermittent inflammatory disorders of the gastrointestinal tract of unknown etiology but a clear genetic predisposition. Prompted by the first investigations on IBD families and twins, the genetic and epigenetic studies have produced an unprecedented amount of information in comparison with other immune ...
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

NUT Carcinoma: Clinicopathologic Features, Molecular Genetics and Epigenetics

open access: yesFrontiers in Oncology, 2022
Nuclear protein in testis (NUT) carcinoma is a rare, highly aggressive, poorly differentiated carcinoma occurring mostly in adolescents and young adults.
Vanessa Moreno   +2 more
doaj   +1 more source

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