Results 71 to 80 of about 50,453 (282)
, 2019 Epigenetic changes are heritable and reversible modifications that significantly affect gene expression without any change in DNA sequence. The epigenetic signature is remodelled during the lifespan as a direct consequence of both environment and ...
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Osteoarthritis year in review: genetics, genomics and epigenetics
, 2023 This “year in review” provides a summary of the research findings on the topic of genetics, genomics and epigenetics for osteoarthritis (OA) between Mar 2021–Apr 2022. A search routine of the literature in PubMed for the keyword, osteoarthritis, together
D. Chan +7 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Genetics and Epigenetics of Arrhythmia and Heart Failure
Frontiers in Genetics, 2013 Heart failure (HF) is the end stage of several pathological cardiac conditions including myocardial infarction, cardiac hypertrophy and hypertension. Various molecular and cellular mechanisms are involved in the development of HF. At the molecular level,
Burcu eDuygu +2 more
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The Genetics and Epigenetics of 22q11.2 Deletion Syndrome
Frontiers in Genetics, 2020 Chromosome 22q11.2 deletion syndrome (22q11.2del) is a complex, multi-organ disorder noted for its varying severity and penetrance among those affected.
Qiumei Du +2 more
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Cancer Genetics and Epigenetics in Cancer Risk Assesment
MCBS (Molecular and Cellular Biomedical Sciences), 2021 Compared to the normal tissues, cancer cells tend to have higher proliferation rate and often lost their ability to undergo apoptosis. In addition, cancer cells can separate themselves from their original tissue thus causing metastasis in other part of ...
Anna Meiliana +2 more
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Hsp90 at the crossroads of genetics and epigenetics [PDF]
Cell Research, 2006 Hsp90 is a specialized molecular chaperone that is capable of buffering the expression of abnormal phenotypes. Inhibition of Hsp90 activity results in the expression of these phenotypes that are otherwise masked. Selection of offspring from the crossing of affected progenies results in inheritance and enrichment of these phenotypes, which can become ...
Keith S K, Wong, Walid A, Houry
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Epigenetic Modification of Genetic Algorithm [PDF]
, 2020 The article presents a new operation in the genetic algorithm. This operation mimics the epigenetic process of cytosine methylation. The Epigenetic processes have a huge impact on the functioning of living organisms, but have not yet been reflected in the operations of genetic algorithms. In a study on the evaluation of the operation mimics epigenetics
Kornel Chrominski +2 more
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Chemical genetics approaches for selective intervention in epigenetics [PDF]
, 2016 Chemical genetics is the use of biologically active small molecules (chemical probes) to investigate the functions of gene products, through the modulation of protein activity.
Chan, Kwok-Ho +5 more
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