Results 101 to 110 of about 283,425 (262)
Demographic model selection using random forests and the site frequency spectrum
Molecular Ecology, 2017 AbstractPhylogeographic data sets have grown from tens to thousands of loci in recent years, but extant statistical methods do not take full advantage of these large data sets. For example, approximate Bayesian computation (ABC) is a commonly used method for the explicit comparison of alternate demographic histories, but it is limited by the “curse of ...
Megan L. Smith +5 more
openaire +3 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Allele rank-frequency spectrum. [PDF]
, 2018 The rank frequency spectrum of alleles at the 59 loci with ≥ 1000 reads. At each rank i, the black lines designate the quintile boundaries of {fi}, the frequencies of the ith most abundant alleles, across loci. The shades of green show simulated quintile
Daniel S. Fisher (3325971) +3 more
core +1 more source
CSEE Journal of Power and Energy SystemsTo accurately diagnose the aging condition of the vehicle-mounted high-voltage cable terminals under the combined electro-thermal stress, this paper proposes a terahertz frequency spectrum technology-based method. First, an electro-thermal aging platform
Binglei Cao +6 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Site frequency spectrum of derived variants. [PDF]
, 2015 (A) The site frequency spectra of 2,983,700 variants classified according to their mutational origin as defined by comparison to the outgroup. Variants are: SW (strong-to-weak; red line; 2,037,148 SNPs in total); WS (weak-to-strong; blue dashed line; 719,
Sylvain Glémin (18118) +2 more
core +1 more source
PLoS ONEThe stochastic finite-fault method based on dynamic corner frequency has been widely applied to simulate high-frequency ground motion of near-fault field. The model input parameters include source term, path term and site condition, many of which exhibit
Xiaohui Jia +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Shock and VibrationIn this study, the loess hill site of an elevated bridge section in Tongwei-Qin’an of the Baolan high-speed railroad was selected as the research object, and the vibration acceleration of the loess hill site under the elevated bridge was tested in the ...
Wujian Yan +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source