Results 81 to 90 of about 30,097,494 (296)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Connecticut State Emergency Response Commission [web site] [Harvested on 2012: Aug. 10]

open access: yes, 2012
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core  

Defence abuse response taskforce: final report [PDF]

open access: yes, 2016
Executive summary The Taskforce was established on 26 November 2012 to assist complainants who had suffered sexual abuse, physical abuse, sexual harassment and workplace harassment and bullying in Defence prior to 11 April 2011.
Defence Abuse Response Taskforce
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Seismic Performance Assessment of an RC Building Due to 2023 Türkiye Earthquakes: A Case Study in Adıyaman, Türkiye

open access: yesBuildings
The 7.7 and 7.6 magnitude Pazarcık and Elbistan earthquakes that struck Kahramanmaraş on 6 February 2023 caused widespread structural damage across many provinces and are considered rare in seismological terms.
Mahmut Bassurucu   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The apparent viscosity to model the behaviour of liquefied sands [PDF]

open access: yesE3S Web of Conferences
The liquefaction induced loss of soil strength and stiffness marks a change of soil state, that switches from solid to liquid. Recently, the research has revealed that when liquefaction is attained, the soil behaves as a non-Newtonian fluid.
Mele Lucia   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sweden's capacity to prepare and respond to a terrorist attack on rail-bound traffic : promising practices and obstacles to inter-organizational collaboration

open access: yes, 2015
This article takes an interest in evolving collaborative practices in crises caused by terrorism targeting rail-bound traffic. Sweden provides the empirical focus, by examining current preparedness processes, this article offers an important perspective ...
Strandh, Veronica,
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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