Results 111 to 120 of about 9,219,803 (286)

Late Bronze Age settlements in the Visun and the Lower Ingulets rivers basin

open access: yesTyragetia, 2020
This work continues the series of publications on Late Bronze Age sites published in the Tyragetia journal in 2018 and 2019. It significantly complements the archaeological map of the late Bronze Age sites of the Black Sea region.
Victor Grebennikov
doaj  

Anatomical Parcellation of Cortical Language Sites [PDF]

open access: yes, 2004
Anatomical labeling of cerebral cortical stimulation (CSM) sites is necessary for intelligent computer querying of a rich and unique experimental database examining neural substrates underlying human language production.
Brinkley, James F   +5 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Lessons from a history of beer canteens and licensed clubs in Indigenous Australian communities [PDF]

open access: yes, 2014
This paper aims to provide historical depth to the idea that alcoholic drinks should be made available in licensed canteens or clubs in discrete Aboriginal communities.
Maggie Brady
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Corporate control? Measuring private sector censorship of social media : a thesis presented in partial fulfilment of the requirements for the degree of Master of Information Science in Information Technology at Massey University, Albany, New Zealand [PDF]

open access: yes, 2016
Censoring activities on sensitive topics have played a significant role on social network sites (SNSs). Owing to the difference in politics, economics and cultures in the various countries, many social network sites including Facebook, Twitter, Google,
Zhong, Hanfeng
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Online 'penny auction' sites: regulation needed [PDF]

open access: yes, 2008
Online 'penny auction' sites allow bidders to win expensive items at a price that appears unbelievably cheap, however users are charged by the site for each bid that they place.
Griffiths, MD
core  

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