Results 1 to 10 of about 45,057 (220)

Inhibition of Phytosterol Biosynthesis by Azasterols

Molecules, 2020
Inhibitors of enzymes in essential cellular pathways are potent probes to decipher intricate physiological functions of biomolecules. The analysis of Arabidopsis thaliana sterol profiles upon treatment with a series of azasterols reveals a specific in ...
Sylvain Darnet, Laetitia B B Martin, Pierre Mercier, Franz Bracher, Philippe Geoffroy, Hubert Schaller   +5 more
doaj   +1 more source

Could Lowering Phytosterol Absorption as Part of Lipid-Lowering Therapy Have a Beneficial Effect on Residual Risk?

Metabolites, 2023
Plant sterols are molecules that are structurally similar to cholesterol and provided only as dietary sources (e.g., vegetables, fruits, nuts, cereals) since they cannot be synthesized by humans.
Panagiotis Anagnostis, Vasileios Kotsis, Maciej Banach, Dimitri P. Mikhailidis   +3 more
doaj   +1 more source

Experimental Study For The Effect of β- Sitosterol on the level of Male,s hormones [PDF]

Kirkuk Journal of Science, 2017
The effect of β-Sitosterol to the levels of male,s hormones was carried out in sera of adult male rabbit, twenty eight of local rabbite, weigh aging range between (800-1500)g.
Esraa Ali Abdul kareem, Dr.Abdul MonaimHamadAl-samarrai   +1 more
doaj   +1 more source

Diatoms synthesize sterols by inclusion of animal and fungal genes in the plant pathway [PDF]

, 2020
Diatoms are ubiquitous microalgae that have developed remarkable metabolic plasticity and gene diversification. Here we report the first elucidation of the complete biosynthesis of sterols in the lineage.
, Angela, d’Ippolito, Giuliana, Fontana, Angelo, GALLO, CARMELA, LANDI, SIMONE, MANZO, EMILIANO, Nuzzo, Genoveffa, Sardo &   +7 more
core   +1 more source

Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol Δ7-reductase in liver and mononuclear leukocytes

Journal of Lipid Research, 1998
Sitosterolemia is a recessively inherited disorder characterized by abnormally increased plasma and tissue plant sterol concentrations. Patients have markedly reduced whole body cholesterol biosynthesis associated with suppressed hepatic, ileal, and ...
Akira Honda, Gerald Salen, Lien B. Nguyen, G. Stephen Tint, Ashok K. Batta, Sarah Shefer   +5 more
doaj   +1 more source

Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum [PDF]

, 2017
Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective: Evaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and ...
Alice Martins, Amélia P. Rauter, Andreia Lopes, Bhandari U, Huang X, José M. F. Nogueira, João Varela, Kilinc M, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Muriach M, Nishishiro M, Nuno R. Neng, Shai LJ, Veerasamy R   +16 more
core   +1 more source

Genetic control of sterol esterification in developing wheat endosperm [PDF]

, 1975
1. 1. The action of gene Pln, previously characterized by the sterol ester patterns of mature whole wheat kernels, has been found to be restricted to the endosperm and not to affect the embryo, the pericarp or the seed coat. 2. 2.
Bush, Carbonero, Clayton, Duperon, Duperon, Duperon, Evers, García-Faure, García-Olmedo, García-Olmedo, Goodwin, Grunwald, Grunwald, Grunwald, Hartman, Heftman, Hendrix, Hølmer, Jennings, Katayama, Kazpryk, Kemp, Lowry, Mudd, Skarsaune, Torres   +25 more
core   +2 more sources

Genetic Control of Serum Marinobufagenin in the Spontaneously Hypertensive Rat and the Relationship to Blood Pressure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundWe have investigated serum levels of immunoreactive marinobufagenin (MBG) in 16‐ to 20‐week‐old spontaneously hypertensive rats (SHRs)‐A3 and in the normotensive Wistar‐Kyoto (WKY) rat strain in the absence of salt loading, and we have ...
Renata I. Dmitrieva, Stacy M. Cranford, Peter A. Doris   +2 more
doaj   +1 more source

Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf. [PDF]

, 2010
U radu je opisana izolacija pet sastojaka petroleterske i diklormetanske frakcije metanolnog ekstrakta kore biljke Delonix regia: lupeol (1), epilupeol (2), β-sitosterol (3), stigmasterol (4) i p-metoksibenzaldehid (5). Nadalje, testirano je antimikrobno
A. Bauer, Abdul Wahab, B. Meyer, B. Vanwagenen, F. Jungalwala, F. Maniruzzaman, G. Morales, Israt Jahan, J. McLaughlin, M. Rahman, Mohammad Islam, Mohammad Kaisar, Mohammad Rahman, Mohammad Rashid, Mohammed Rahman, O. Lawal, R. Harish, U. Kolak, Y. Aratanechemuge   +18 more
core   +3 more sources

Steroidal Triterpenes: Design of Substrate-Based Inhibitors of Ergosterol and Sitosterol Synthesis

Molecules, 2009
This article reviews the design and study, in our own laboratory and others, of new steroidal triterpenes with a modified lanosterol or cycloartenol frame.
Jialin Liu, William David Nes
doaj   +1 more source