β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice [PDF]
The Journal of Nutrition, 2004 We hypothesized that the phytosterols beta-sitosterol (BSS), beta-sitosterol glucoside (BSSG), and Moducare (MC; BSS:BSSG = 99:1) could modulate the growth of estrogen-dependent human breast cancer cells in vitro and in vivo. The present study evaluated the estrogenic and antiestrogenic effects of BSS, BSSG, and MC (0.001 to 150 micromol/L) on the ...
Young H, Ju +4 more
openaire +3 more sources
Selenium Dehydrogenation of Sitosterol [PDF]
Nature, 1933 WE have reported1 that the selenium dehydrogena-tion of cholesterol C27H46O and ergosterol C28H44O gives two different hydrocarbons, C25H24, m.p. 225°, and C26H26, m.p. 214°, respectively, while Diels and Karstens2 claimed the formation of only one product, C25H24, m.p. 220°, from both sterols.
L. RUZICKA +3 more
openaire +2 more sources
A novel approach to enhance beta-sitosterol bioavailability isolated from <i>Jurinea macrocephala</i> (a high-altitude) plant in biodegradable chitosan against lung cancer. [PDF]
Front OncolSangral M, Singh A, Gupta A, Bhagat M.
europepmc +3 more sources
β-Sitosterol: An Antibacterial Agent in Aquaculture Management of Vibrio Infections
Journal of Pure and Applied Microbiology, 2020 This study aims at investigation of antibacterial property of Parthenium hysterophorous against aquatic bacterial pathogens and to identify the key bioactive compound of the same.
Lokesh Ravi +3 more
doaj +1 more source
Activity Against Pythium insidiosum and Isolated Constituents of Cordia insignis Roots. [PDF]
Chem BiodiversThis study investigates the roots of Cordia insignis in search of novel treatments for pythiosis, caused by the oomycete Pythium insidiosum. Seven compounds are isolated, including steroids, a saponin, a coumarin, a fatty acid, and a glycoside, the latter two are reported for the first time in the genus.
de Oliveira RC +8 more
europepmc +2 more sources
Journal of Lipid Research, 2004 The objective of this study was to measure the effects on serum lipids and plasma phytosterols of 6.6 g/day phytosterols from three foods (bread, breakfast cereal, and spread) consumed for 12 weeks compared with a diet that was not enriched with ...
Peter M. Clifton +5 more
doaj +1 more source
Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe
Journal of Lipid Research, 2005 Consumption of plant sterols and treatment with ezetimibe both reduce cholesterol absorption in the intestine. However, the mechanism of action differs between the two treatments, and the consequences of combination treatment are unknown.
Lily Jakulj +5 more
doaj +1 more source
β-Sitosterol Inhibits The Proliferation of Endometrial Cells via Regulating Smad7-Mediated TGF-β/Smads Signaling Pathway [PDF]
Cell Journal, 2023 Objective: To investigate the effect of β-sitosterol on endometrial cells to understand the underlying mechanism.Materials and Methods: This is a laboratory-based experimental study conducted on animals and cells.
Yi Wen +6 more
doaj +1 more source
Journal of Lipid Research, 2009 Changes in the balance of cholesterol absorption and synthesis and moderately elevated plasma plant sterols have been suggested to be atherogenic. Measuring cholestanol, lathosterol, campesterol, and sitosterol, we investigated the relationships of ...
Guenther Silbernagel +7 more
doaj +1 more source
ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile
Journal of Lipid Research, 2005 The major pathway for the removal of cholesterol from the body is via secretion into the bile. Three members of the ATP binding cassette (ABC) family, ABCG5 (G5), ABCG8 (G8), and ABCB4 (MDR2), are required for the efficient biliary export of sterols ...
Silvia Langheim +6 more
doaj +1 more source