Results 41 to 50 of about 61,274 (258)

Commentary: Situated learning in the Network society

open access: yesSeminar.net, 2008
There is a need to develop a broader view of knowledge for dealing with the way in which new digital trends influence the underlying conditions for schools, pedagogy and subjects.
Rune Krumsvik
doaj  

Shifting relationships with nature through schools: exploring the social and spatial context for transformative sustainability education

open access: yesEcology and Society
Transformative sustainability education has emerged as a vital approach for addressing the value crisis at the root of biodiversity loss, climate change, and socio-environmental injustices in the Anthropocene.
Matteo Giusti   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

APRENDIZAGEM SITUADA

open access: yesTexto Livre: Linguagem e Tecnologia, 2014
One goal of STIS (Interdisciplinary Theoretical Seminars of Semiotec ) is to discuss at a conference on a theoretical topic of one of the areas of expertise and research of Texto Livre Group: Semiotics and Technology aimed an interdisciplinary audience ...
Elizabeth Guzzo de Almeida
doaj  

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Identity Formation through Brokering in Scientific Practice

open access: yesOutlines, 2003
Inspired by recent theorization by Dreier and Lave concerning situated perspectives on learning, I illuminate learning of international graduate students in a science lab in Japan as trajectories of participation in multi-layered activities and various ...
Rieko Sawyer
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Rereading Jean Lave 30 years on: Analogy and transfer-in-pieces

open access: yesNordic Studies in Education, 2020
This paper explores and evaluates some of the criticisms of a cognitive approach to learning leveled by Lave in Cognition in Practice (1988). The paper progresses by initially identifying learning transfer as the focal topic of Lave’s work.
Stig Børsen Hansen
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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