Results 21 to 30 of about 290,074 (337)

Size exclusion chromatography as green support for forced degradation study of adalimumab

Acta Pharmaceutica, 2023
Size exclusion chromatography (SEC) has become a powerful tool for analysing size variants of biologic drugs in their native form. Modern SEC can be defined by the use of chromatographic columns packed with sub-3 µm particles, allowing an increase in ...
Kovačić Jelena, Klarić Daniela Amidžić, Turk Nikša, Mornar Ana   +3 more
doaj   +1 more source

Uncertainty of Size-Exclusion Chromatography Method in Quality Control of Bevacizumab Batches

Separations, 2021
In addition to the analytical challenges related to the size and complexity of biopharmaceutical drugs, the inherent variability that arises due to their manufacturing process requires monitoring throughout the production process to ensure the safety and
Alexis Oliva, Matías Llabrés
doaj   +1 more source

HEMA/MMA/EDMA packing material evaluation for size exclusion chromatography (SEC)

Materials Research, 2005
HEMA/MMA/EDMA (2-hydroxyethyl methacrylate/methyl methacrylate/ethyleneglycol methacrylate) copolymer beads have been synthesized for use in aqueous SEC.
Cristina Duarte Vianna-Soares, Kim Cherng-Ju, Michael Robert Borenstein   +2 more
doaj   +1 more source

Molar mass and solution conformation of branched alpha(1 - 4), alpha(1 - 6) Glucans. Part I: Glycogens in water [PDF]

, 2008
Solution molar masses and conformations of glycogens from different sources (rabbit, oyster, mussel and bovine) were analysed using sedimentation velocity in the analytical ultracentrifuge, size-exclusion chromatography coupled to multi-angle laser light
Ang, S., Harding, S. E., Hill, S. E., Lewis, S., Morris, Gordon, Nobbmann, U., Schafer, B.   +6 more
core   +1 more source

Determination of Hydrodynamic Radius of Proteins by Size Exclusion Chromatography

Bio-Protocol, 2017
Size exclusion chromatography (SEC) or gel filtration is a hydrodynamic technique that separates molecules in solution as a function of their size and shape. In the case of proteins, the hydrodynamic value that can be experimentally derived is the Stokes
Valentina La Verde, Paola Dominici, Alessandra Astegno   +2 more
doaj   +1 more source

Direct iminization of PEEK [PDF]

, 2011
Semi-crystalline poly(ether ketone)s are important high-temperature engineering thermoplastics, but are difficult to characterize at the molecular level because of their insolubility in conventional organic solvents.
Attwood T. E., Bishop M. T., Colquhoun H. M., Colquhoun H. M., Colquhoun H. M., Daoust D., Daoust D., Daoust D., Devaux J., Hergenrother P. M., Howard M. Colquhoun, Ioannis Manolakis, Lindfors B. E., Mohanty D. K., Paul Cross, Staniland P. A., Teasley M. F., Teasley M. F.   +17 more
core   +1 more source

The Use of Size Exclusion Chromatography to Monitor Protein Self-Assembly

Crystals, 2017
High resolution size exclusion chromatography (SEC) coupled with static light scattering (SLS) analyses were conducted to study the effect of the mobile phase ionic strength and protein concentration on the output of SEC experiments.
Alaa Adawy, Matthew R. Groves
doaj   +1 more source

Isolation of small extracellular vesicles from regenerating muscle tissue using tangential flow filtration and size exclusion chromatography. [PDF]

Skelet Muscle
Gurriaran-Rodriguez U, De Repentigny Y, Kothary R, Rudnicki MA.   +3 more
europepmc   +3 more sources

Three method-combination protocol for improving purity of extracellular vesicles [PDF]

, 2020
Extracellular vesicles (EVs) are nanosized structures able to carry proteins, lipids and genetic material from one cell to another with critical implications in intercellular communication mechanisms.
Giamas, Georgios, Kumaran, Anish, Simon, Thomas, Veselu, Diana-Florentina   +3 more
core   +1 more source

The influence of bovine serum albumin on β-lactoglobulin denaturation, aggregation and gelation [PDF]

, 2006
peer-reviewedThe effect of bovine serum albumin (BSA) on the heat-induced denaturation, aggregation and subsequent acid-induced gelation of β-lactoglobulin (β-lg) was investigated in this work.
Brodkorb, Andre, Kehoe, Joseph James, Morris, Edwin R   +2 more
core   +1 more source