Uncertainty of Size-Exclusion Chromatography Method in Quality Control of Bevacizumab Batches
Separations, 2021 In addition to the analytical challenges related to the size and complexity of biopharmaceutical drugs, the inherent variability that arises due to their manufacturing process requires monitoring throughout the production process to ensure the safety and
Alexis Oliva, Matías Llabrés
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Molar mass and solution conformation of branched alpha(1 - 4), alpha(1 - 6) Glucans. Part I: Glycogens in water [PDF]
, 2008 Solution molar masses and conformations of glycogens from different sources (rabbit, oyster, mussel and bovine) were analysed using sedimentation velocity in the analytical ultracentrifuge, size-exclusion chromatography coupled to multi-angle laser light
Ang, S. +6 more
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Determination of Hydrodynamic Radius of Proteins by Size Exclusion Chromatography
Bio-Protocol, 2017 Size exclusion chromatography (SEC) or gel filtration is a hydrodynamic technique that separates molecules in solution as a function of their size and shape. In the case of proteins, the hydrodynamic value that can be experimentally derived is the Stokes
Valentina La Verde +2 more
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The Use of Size Exclusion Chromatography to Monitor Protein Self-Assembly
Crystals, 2017 High resolution size exclusion chromatography (SEC) coupled with static light scattering (SLS) analyses were conducted to study the effect of the mobile phase ionic strength and protein concentration on the output of SEC experiments.
Alaa Adawy, Matthew R. Groves
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The influence of bovine serum albumin on β-lactoglobulin denaturation, aggregation and gelation [PDF]
, 2006 peer-reviewedThe effect of bovine serum albumin (BSA) on the heat-induced denaturation, aggregation and subsequent acid-induced gelation of β-lactoglobulin (β-lg) was investigated in this work.
Brodkorb, Andre +2 more
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Direct iminization of PEEK [PDF]
, 2011 Semi-crystalline poly(ether ketone)s are important high-temperature engineering thermoplastics, but are difficult to characterize at the molecular level because of their insolubility in conventional organic solvents.
Attwood T. E. +17 more
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Three method-combination protocol for improving purity of extracellular vesicles [PDF]
, 2020 Extracellular vesicles (EVs) are nanosized structures able to carry proteins, lipids and genetic material from one cell to another with critical implications in intercellular communication mechanisms.
Giamas, Georgios +3 more
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Glycan analysis of the chicken synaptic plasma membrane glycoproteins - a major synaptic N-glycan carries the LewisX determinant [PDF]
, 2005 The majority of plasma membrane components are glycosylated. It is now widely accepted that this post-translational modification is crucial during the establishment, maintenance and function of the nervous system.
Koles, Kate +3 more
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Biospeciation of Cr(III) Nutritional Supplements in Biological Fluids
Makara Journal of Science, 2017 Metal ion speciation in various biological systems has been extensively studied to elucidate its biological role and the toxicity of the element of interest.
Anna Safitri, Aviva Levina, Peter A. Lay
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Biological Procedures Online, 2020 Background Circulating small extracellular vesicles (sEVs) and its associated proteins are of great interest in the early detection of many diseases. However, there is no gold standard for plasma sEVs isolation, especially for proteomic profiling which ...
Rui Wei +6 more
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