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The Pharmacological Management of Skeletal-Related Events From Metastatic Tumors

Orthopedics, 2009
Bone is one of the most common sites of metastatic disease from cancer, affecting around 400,000 patients each year. Skeletal-related events (SRE) include hypercalcemia, fractures, spinal cord compression or severe bone pain and may occur as a complication of metastasis.
Anna, Hitron, Val, Adams
openaire   +2 more sources

Predicting Skeletal-related Events Using SINS

Spine
Study Design. Predictive study utilized retrospectively collected data. Objective. The primary objective was to evaluate the predictive association between the Spine Instability Neoplastic Score (SINS) and Skeletal-related events (SREs).
Kazuo, Nakanishi   +6 more
openaire   +2 more sources

Impact of skeletal-related events on multiple myeloma treatment.

Journal of Clinical Oncology, 2018
e20009Background: Skeletal-related events (SREs), sequelae of bone lesions, are common and devastating complications in patients with multiple myeloma (MM).This study assessed the impact of SREs on...
Debajyoti Bhowmik   +5 more
openaire   +1 more source

Skeletal-Related Events In Myeloma: A Population-Based Study

Blood, 2013
Abstract Introduction New therapies have resulted in improvements in myeloma survival, with increasing numbers of patients receiving treatment over several years. Despite this progress, the remitting and relapsing course of the disease continues to be associated with increases in patient morbidity and
John Ashcroft   +9 more
openaire   +1 more source

Patients with SMARCA4-deficient thoracic sarcoma and severe skeletal-related events

Lung Cancer, 2019
SMARCA4-deficient thoracic sarcoma(DTS) is a recently identified new entity of thoracic malignancies characterized by inactivation of SMARCA4. Patients with SMARCA4-DTS have a particulary aggresive clinical course and no effective treatments. However, the detailed clinical features of SMARCA4-DTS remain unclear. Here, we report the clinical courses and
Kei Kunimasa   +11 more
openaire   +2 more sources

Opioid Use Among Metastatic Prostate Cancer Patients With Skeletal-related Events

Clinical Therapeutics, 2016
The development of skeletal-related events (SREs) (pathologic fracture, need for surgery and/or radiation to bone, spinal cord compression, and hypercalcemia of malignancy) in metastatic prostate cancer (MPC) is associated with worsened pain and compromised quality of life. Opioids are frequently used throughout the course of SRE treatment.
Avin, Yaldo   +8 more
openaire   +2 more sources

Canadian Health Care Institution Resource Utilization Resulting From Skeletal-Related Events

Hospital Practice, 2014
We describe the types of major institution health care resources consumed as a result of skeletal-related events (SREs) [ie, pathological fracture, bone surgery, radiation to bone, spinal cord compression].A retrospective multicenter chart review of cancer patients with bone metastases who experienced SREs was conducted.
Mohdhar J, Habib   +3 more
openaire   +2 more sources

[Predictive factors for skeletal-related events in lung cancer].

Revue des maladies respiratoires, 2020
Skeletal-related events (SRE) are common in patients with bone metastatic lung cancer and have a negative impact on quality of life and survival. The objective of this study is to identify predictive factors for SRE occurrence among this population.We conducted a 3-year retrospective study including 100 lung cancer patients with bone metastasis.Eighty ...
A, Villemain   +6 more
openaire   +1 more source

Costs of multiple myeloma and associated skeletal-related events in The Netherlands

Expert Review of Pharmacoeconomics & Outcomes Research, 2004
Multiple myeloma causes significant skeletal morbidity (e.g., pain and pathologic fractures) resulting from osteolytic lesions, and the associated medical costs can be considerable. Therefore, the authors of this review conducted a retrospective cost analysis to quantify the medical costs associated with skeletal complications in patients treated for ...
Groot, MT (Martijn)   +3 more
openaire   +2 more sources

Impact of denosumab on skeletal-related events in solid tumors.

Journal of Clinical Oncology, 2018
e18754Background: Skeletal-related events (SRE) are frequent consequences of bone metastases from solid tumours like breast, prostate and lung.
Sridevi Rajeeve   +4 more
openaire   +1 more source

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