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The Pharmacological Management of Skeletal-Related Events From Metastatic Tumors
Orthopedics, 2009Bone is one of the most common sites of metastatic disease from cancer, affecting around 400,000 patients each year. Skeletal-related events (SRE) include hypercalcemia, fractures, spinal cord compression or severe bone pain and may occur as a complication of metastasis.
Anna, Hitron, Val, Adams
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Predicting Skeletal-related Events Using SINS
SpineStudy Design. Predictive study utilized retrospectively collected data. Objective. The primary objective was to evaluate the predictive association between the Spine Instability Neoplastic Score (SINS) and Skeletal-related events (SREs).
Kazuo, Nakanishi +6 more
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Impact of skeletal-related events on multiple myeloma treatment.
Journal of Clinical Oncology, 2018e20009Background: Skeletal-related events (SREs), sequelae of bone lesions, are common and devastating complications in patients with multiple myeloma (MM).This study assessed the impact of SREs on...
Debajyoti Bhowmik +5 more
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Skeletal-Related Events In Myeloma: A Population-Based Study
Blood, 2013Abstract Introduction New therapies have resulted in improvements in myeloma survival, with increasing numbers of patients receiving treatment over several years. Despite this progress, the remitting and relapsing course of the disease continues to be associated with increases in patient morbidity and
John Ashcroft +9 more
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Patients with SMARCA4-deficient thoracic sarcoma and severe skeletal-related events
Lung Cancer, 2019SMARCA4-deficient thoracic sarcoma(DTS) is a recently identified new entity of thoracic malignancies characterized by inactivation of SMARCA4. Patients with SMARCA4-DTS have a particulary aggresive clinical course and no effective treatments. However, the detailed clinical features of SMARCA4-DTS remain unclear. Here, we report the clinical courses and
Kei Kunimasa +11 more
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Opioid Use Among Metastatic Prostate Cancer Patients With Skeletal-related Events
Clinical Therapeutics, 2016The development of skeletal-related events (SREs) (pathologic fracture, need for surgery and/or radiation to bone, spinal cord compression, and hypercalcemia of malignancy) in metastatic prostate cancer (MPC) is associated with worsened pain and compromised quality of life. Opioids are frequently used throughout the course of SRE treatment.
Avin, Yaldo +8 more
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Canadian Health Care Institution Resource Utilization Resulting From Skeletal-Related Events
Hospital Practice, 2014We describe the types of major institution health care resources consumed as a result of skeletal-related events (SREs) [ie, pathological fracture, bone surgery, radiation to bone, spinal cord compression].A retrospective multicenter chart review of cancer patients with bone metastases who experienced SREs was conducted.
Mohdhar J, Habib +3 more
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[Predictive factors for skeletal-related events in lung cancer].
Revue des maladies respiratoires, 2020Skeletal-related events (SRE) are common in patients with bone metastatic lung cancer and have a negative impact on quality of life and survival. The objective of this study is to identify predictive factors for SRE occurrence among this population.We conducted a 3-year retrospective study including 100 lung cancer patients with bone metastasis.Eighty ...
A, Villemain +6 more
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Costs of multiple myeloma and associated skeletal-related events in The Netherlands
Expert Review of Pharmacoeconomics & Outcomes Research, 2004Multiple myeloma causes significant skeletal morbidity (e.g., pain and pathologic fractures) resulting from osteolytic lesions, and the associated medical costs can be considerable. Therefore, the authors of this review conducted a retrospective cost analysis to quantify the medical costs associated with skeletal complications in patients treated for ...
Groot, MT (Martijn) +3 more
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Impact of denosumab on skeletal-related events in solid tumors.
Journal of Clinical Oncology, 2018e18754Background: Skeletal-related events (SRE) are frequent consequences of bone metastases from solid tumours like breast, prostate and lung.
Sridevi Rajeeve +4 more
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