A non-linear approach to modelling of electrically stimulated skeletal muscle [PDF]
, 2001 This paper is concerned with the development and analysis of a nonlinear approach to modeling of the contraction of electrically stimulated skeletal muscle.
Gollee, H. +2 more
core +8 more sources
Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance? [PDF]
, 2010 <p><b>Background:</b> South Asians are more insulin resistant than Europeans, which cannot be fully explained by differences in adiposity. We investigated whether differences in oxidative capacity and capacity for fatty acid utilisation
Nita G Forouhi +45 more
core +1 more source
Regulation of skeletal muscle plasticity by the transcriptional coregulators PGC-1α and NCoR1 [PDF]
, 2013 Skeletal muscle plasticity is regulated by a wide range of factors, among which environmental stimuli such as exercise play a central role. Importantly, changes in skeletal muscle phenotype exert a direct impact on health and risk to premature death.
Pérez-Schindler, Joaquín
core +1 more source
Skeletal muscle mTORC1 regulates whole-body metabolism [PDF]
, 2015 Skeletal muscle, which represents over 40% of the total body mass, is a dynamic tissue with a key role in the maintenance of metabolic homeostasis. Several lines of evidence indicate that alterations of the normal muscle function, as for example in ...
Ormazabal, Maitea Guridi
core +1 more source
Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]
, 1990 An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Quasthoff, Stefan +7 more
core +1 more source
Mouse skeletal muscle fiber-type-specific macroautophagy and muscle wasting are regulated by a Fyn/STAT3/Vps34 signaling pathway [PDF]
, 2012 Skeletal muscle atrophy induced by aging (sarcopenia), inactivity, and prolonged fasting states (starvation) is predominantly restricted to glycolytic type II muscle fibers and typical spares oxidative type I fibers.
Bastie, Claire C. +12 more
core +1 more source
Complex coordination of cell plasticity by a PGC-1α-controlled transcriptional network in skeletal muscle [PDF]
, 2015 Skeletal muscle cells exhibit an enormous plastic capacity in order to adapt to external stimuli. Even though our overall understanding of the molecular mechanisms that underlie phenotypic changes in skeletal muscle cells remains poor, several factors ...
Handschin, Christoph +5 more
core +1 more source
Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor gamma coactivator 1alpha [PDF]
, 2010 Exercise triggers a pleiotropic response in skeletal muscle, which results in a profound remodeling of this tissue. Physical activity-dependent muscle fiber plasticity is regulated by a number of distinct signaling pathways.
Handschin, C.
core +1 more source
New insights in the regulation of skeletal muscle PGC-1α by exercise and metabolic diseases [PDF]
, 2013 Skeletal muscle energy metabolism is severely impaired in insulin resistant and type 2 diabetic patients. In particular, deregulated transcription of oxidative metabolism genes has been linked to the development of non-communicable metabolic diseases ...
Handschin, Christoph +1 more
core +1 more source
The Scientific World Journal, 2013 In the beginning of the last century, muscle proteins were viewed as static structural molecules not capable of being utilized by other tissues or organs. This concept was accepted until the 30s, where Rudolf Schoenheimer presented strong evidences about the “Dynamic State of Body Constituents,” which means that skeletal muscle is not only capable of ...
Lucas Guimarães-Ferreira +3 more
openaire +3 more sources